The future of contactless care: robotic systems gain patient approval

WHO: Giovanni Traverso, MB, BChir, PhD, Associate Physician, Division of Gastroenterology, Brigham and Women’s Hospital; corresponding author of a new article published in JAMA Network Open. Peter Chai, MD, MMS, Assistant Professor, Department of Emergency Medicine, Brigham and Women’s Hospital; first author. WHAT: In the age of COVID-19, mobile robotic telehealth systems could help clinicians…

Molecular mechanisms identified in chronic skin inflammation

Frequently occurring chronic skin inflammation like in atopic dermatitis (AD or neurodermatitis) and psoriasis have different causes such as genetic predisposition, stress or allergens. These frequently occurring skin diseases are mostly attributed by biomedical scientists to a disturbed immune system, although the noticeable thickening and flaking of the epidermis, which is the outermost layer of…

Automatic adverse drug reaction extraction from electronic health records

Patients’ electronic health records convey crucial information. The application of natural language processing techniques to these records may be an effective means of extracting information that may improve clinical decision making, clinical documentation and billing, disease prediction and the detection of adverse drug reactions. Adverse drug reactions are a major health problem, resulting in hospital…

BCAS3-C16orf70 complex is a new actor on the mammalian autophagic machinery

Autophagy is an intracellular degradation process of cytosolic materials and damaged organelles. Researchers at Ubiquitin Project of TMIMS have been studying the molecular mechanism of mitophagy, the selective autophagy process to eliminate damaged mitochondria. PINK1 (a serine/threonine kinase) and Parkin (a ubiquitin ligating enzyme: E3) work together to ubiquitylate the outer membrane proteins of damaged…

Eight ways chemical pollutants harm the body

A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations and mutations, epigenetic alterations, mitochondrial dysfunction, endocrine disruption, altered intercellular communication, altered microbiome communities, and impaired nervous system function. The study by researchers at Columbia University…