Comprehensive clinical sequencing opens door to the promise of precision medicine

IMAGE: Co-corresponding authors Jinghui Zhang, Ph.D., St. Jude Department of Computational Biology chair, demonstrated that comprehensive genomic sequencing of all pediatric cancer patients is feasible and essential to capitalize on the… view more  Credit: St. Jude Children’s Research Hospital St. Jude Children’s Research Hospital investigators have demonstrated that comprehensive genomic sequencing of all pediatric cancer patients…

New insights into immune responses to malaria

Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically. An international team used mass cytometry – an in-depth way of characterising individual cells – and machine learning to discover ‘immune signatures’ associated with…

UMass Amherst grad student awarded fellowship for food allergy research

IMAGE: Cassandra Suther is a UMass Amherst food science Ph.D. candidate. view more  Credit: UMass Amherst University of Massachusetts Amherst food science Ph.D. candidate Cassandra Suther has received a prestigious predoctoral fellowship of $180,000 from the U.S. Department of Agriculture’s National Institute of Food and Agriculture (USDA-NIFA) to study the effect of norovirus on the development…

Bacteria navigate on surfaces using a ‘sense of touch’

Many disease-causing bacteria such as Pseudomonas aeruginosa crawl on surfaces through a walk-like motility known as “twitching”. Nanometers-wide filaments called type IV pili are known to power twitching, but scientists ignore which sensory signals coordinate the microbes’ movements. Now, EPFL researchers have found that Pseudomonas bacteria use a mechanism similar to our sense of touch…