Fentanyl use by people who use drugs has doubled since 2015, and two-thirds of people are aware they’ve taken it, finds new research out of British Columbia, the Canadian province that has experienced the highest number of illicit drug toxicity deaths as a result of the opioid crisis. The findings point to the importance of…
Stanford scientists have completed the first global census of diverse proteins sprouting tree-like from the outer membrane of a cell. These cell surface proteins govern how cells interact with one another and how they assemble into tissues and organs such as hearts and brains. “Cell architecture is determined by cell-cell interactions, and these interactions are…
Biomedical data scientists at the Stanford University School of Medicine have shown that the number of genes a cell uses to make RNA is a reliable indicator of how developed the cell is, a finding that could make it easier to target cancer-causing genes. Cells that initiate cancer are thought to be stem cells, which…
There remains a controversy in scientific circles today regarding the value of lithium therapy in treating Alzheimer’s disease. Much of this stems from the fact that because the information gathered to date has been obtained using a multitude of differential approaches, conditions, formulations, timing and dosages of treatment, results are difficult to compare. In addition,…
“Jumping genes” — bits of DNA that can move from one spot in the genome to another — are well-known for increasing genetic diversity over the long course of evolution. Now, new research at Washington University School of Medicine in St. Louis indicates that such genes, also called transposable elements, play another, more surprising role:…
Reno, Nev. – To better understand the organization of the brain and the perceptual tendencies in humans, a team of four scientists are recording video from four head-mounted cameras – with eyetracking and head movement – and assembling a massive video database with more than 240 hours of first-person video that can be used by…
HOBOKEN, N.J.–January 24, 2020– John Wiley & Sons Inc. (NYSE: JW-A) (NYSE: JW-B), a global leader in research and education, will provide free access to all articles related to the coronavirus in support of the outbreak relief efforts in China. Wiley has identified 54 relevant articles. These important pieces of literature will remain free until…
Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction. In a new study, published Jan. 14, 2020 in PNAS, researchers at University of California San Diego School of Medicine found that opioid dependence produced permanent changes in the brains…
Particularly in the case of accelerated drug approvals and drugs for rare diseases (orphan drugs), the evidence available at the time of market access is often insufficient for the early benefit assessment of drugs. Often, the studies are too short or no data on patient-relevant outcomes were collected. Comparisons with the German standard of care…
London, UK: A new study published in the journal Cephalalgia, the official journal of the International Headache Society, shows unprecedented data regarding the neuroanatomical influence on the treatment response of patients with trigeminal neuralgia. The study, entitled “Hippocampal and trigeminal nerve volume predict outcome of surgical treatment for trigeminal neuralgia”, was conducted by Dr. Tejas…