Intratumoral heterogeneity may be responsible for chemotherapy resistance in patients with small cell lung cancer

HOUSTON – Small cell lung cancer (SCLC) accounts for 14% of all lung cancers and is often rapidly resistant to chemotherapy, resulting in poor clinical outcomes. Treatment has changed little for decades, but a study at The University of Texas MD Anderson Cancer Center found that chemotherapy results in increased heterogeneity within the tumor, leading…

The Lancet Psychiatry: Life-course-persistent antisocial behaviour may be associated with differences in brain structure

MRI brain scans suggest there are characteristic differences in brain structure of individuals who exhibit life-course-persistent antisocial behaviour. Individuals who exhibit life-course-persistent antisocial behaviour – for example, stealing, aggression and violence, bullying, lying, or repeated failure to take care of work or school responsibilities – may have thinner cortex and smaller surface area in regions…

Coronavirus Live Updates: U.S. Cruise Ship Passengers Evacuated From Japan; Taiwan Reports First Death

Here’s what you need to know: Flights carrying American passengers from a cruise ship took off from Japan. ImageThe Daikoku Pier Cruise Terminal, where the Diamond Princess is docked in Yokohama, Japan, south of Tokyo.Credit…Franck Robichon/EPA, via Shutterstock American passengers evacuated a cruise ship that has been quarantined for more than a week in the…

Examining how often care, ICU admissions were consistent with treatment-limiting orders near end of life

What The Study Did: Patients with chronic life-limiting illnesses often have medical orders with treatment limitations in place regarding medical interventions and intensive care unit admissions near the end of their lives. This observational study included about 1,800 patients with such orders who were hospitalized within six months of their death to examine how often…

The End of Australia as We Know It

SYDNEY, Australia — In a country where there has always been more space than people, where the land and wildlife are cherished like a Picasso, nature is closing in. Fueled by climate change and the world’s refusal to address it, the fires that have burned across Australia are not just destroying lives, or turning forests…