New longitudinal study documents antibody responses to COVID-19 5 months after symptom onset

A new 5-month longitudinal analysis of 254 COVID-19 patients who displayed a wide range of disease severity – from asymptomatic to deadly illness – suggests that IgA and IgM antibodies to the SARS-CoV-2 virus disappear quickly during convalescence. IgG antibodies likely persist for longer, but Katharina Röltgen and colleagues nonetheless documented a slow, inexorable decline…

The Elderly vs. Essential Workers: Who Should Get the Coronavirus Vaccine First?

In September, academic researchers analyzed the Department of Homeland Security’s list of essential workers and found that it broadly mirrored the demographics of the American labor force. The researchers proposed a narrower, more vulnerable category — “frontline workers,” such as food deliverers, cashiers and emergency medical technicians, who must work face to face with others…

Integrated anemia-SCD test demonstrates accurate results in study at 2020 ASH meeting

Researchers from Case Western Reserve University presented research today in which Hemex Health’s Gazelle platform diagnostic technology successfully tested 46 patients with 100% sensitivity and over 92.3% specificity for anemia and with 100% accuracy for hemoglobin variants. The preliminary study included blood samples collected from Cleveland-area patients studied for anemia and sickle cell disease. The…

CAR T-cell therapy found highly effective in patients with high-risk non-Hodgkin lymphoma

A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical trial, Dana-Farber Cancer Institute investigators report at the virtual 62nd American Society of Hematology (ASH) Annual Meeting. While NHL tends to be a slow-growing disease,…