Led by an expert international Editorial Advisory Board, Future Drug Discovery is a peer-reviewed, open access journal covering the latest breakthrough science in drug discovery, research & development. “The field of drug discovery has historically been troubled by high failure rates, and multidisciplinary research and access to data are being increasingly embraced in order to…
Encapsulating human stem-cell-derived beta cells in microcapsules made with a protein that repels key immune cells restored glucose metabolism in diabetic mice and protected the cells from immune system attack, preventing the buildup of inflammatory fibrotic tissue that has plagued previous trials of encapsulated beta cells. A team of Massachusetts General Hospital (MGH) investigators reports…
Duke University will pay $112.5 million to the federal government to settle allegations that researchers submitted applications and reports containing falsified data to win more than two dozen grants from the National Institutes of Health and the Environmental Protection Agency, the Justice Department said on Monday. “Taxpayers expect and deserve that federal grant dollars will…
Two of the country’s leading medical groups on Monday issued a call to arms against the soda industry, urging legislators and policymakers to embrace taxes, warning labels and advertising restrictions to deter young people from consuming the sugary beverages that are increasingly linked to the nation’s crisis of obesity and chronic disease. Describing sweetened drinks…
In London this weekend, visitors to the Old Royal Naval College headed to its reopened “painted hall,” an ornate masterpiece called Britain’s answer to the Sistine Chapel, and then went to the Sackler Gallery to learn its story. In Paris, at the Louvre, lovers of Persian art knew there was only one place to go:…
In June 2017 Kimberlee Moran, a forensic scientist at Rutgers University-Camden, stood in a pit at a construction site in downtown Philadelphia, just across from the Betsy Ross House. The walls of the pit were shored up by diagonal pillars of dirt. They bristled with coffin wood — and human bones. But what she couldn’t…
Pot brownies and other cannabis “edibles” like gummy bears that are sold online and where marijuana is legal may seem like harmless fun, but new research indicates that edibles may be more potent and potentially more dangerous than pot that is smoked or vaped. The new study analyzed thousands of cannabis-triggered emergency room visits in…
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Johnson & Johnson and Bayer said on Monday that they had agreed to pay $775 million to settle about 25,000 lawsuits involving the blood thinner Xarelto, which they jointly sell. The settlement, which will be split evenly between the two companies, resolves state and federal cases in which patients sued the companies for failing to…
As a child growing up in the Netherlands, Hanna ten Brink spent many days lingering by a pond in her family’s garden, fascinated by metamorphosis. Tadpoles hatched from eggs in the pond and swam about, sucking tiny particles of food into their mouths. After a few weeks, the tadpoles lost their tails, sprouted legs and…