Reported Coronavirus Cases Top 5 Million Worldwide

Here’s what you need to know: ImageA family, wearing protective equipment at a Srinagar graveyard in the Kashmir Valley on Thursday, offered prayers for a woman who died of Covid-19.Credit…Tauseef Mustafa/Agence France-Presse — Getty Images A million new infections were confirmed in less than two weeks. More than five million people worldwide have contracted the coronavirus,…

‘Jaw-Dropping’ Fraud Reported as Jobless Claims Reach 38.6 Million

Here’s what you need to know: ImageVolunteers with the Los Angeles Unified School District provided meals to families in their community at a drive-by grab-and-go on Monday.Credit…Ryan Young for The New York Times A fraud network siphoned hundreds of millions of dollars in unemployment funds. A sophisticated fraud network targeting Washington State’s unemployment system claimed…

Anti-obesity medications mitigate weight regain in RYGB surgery patients

SILVER SPRING, Md.–Researchers have discovered that anti-obesity medications such as phentermine and topiramate, used individually or in combination, can significantly reduce weight regain in patients after Roux-en-Y gastric bypass surgery, according to a retrospective study published online in Obesity, the flagship journal of The Obesity Society. “Our study provides evidence that medications can help, especially…

Large-scale analysis of protein arginine methylation by mass spectrometry

Methylation (namely addition of a methyl group) of arginine amino acid residues of proteins is a post-translational modification (PTM) catalyzed by a family of nine enzymes called Protein Arginine Methyl-Transferases (PRMTs). PRMTs have been gaining increasing attention in the scientific landscape due their role in several essential physiological processes and implication in various diseases, including…

When developing vaccines against COVID-19, ‘fast is slow, and slow is fast’

Bypassing clinical trials for a potential SARS-CoV-2 vaccine would be “catastrophic,” says Science Advances deputy editor Douglas Green in this Editorial. Instead, it’s vital to take time to ensure any vaccine candidate’s safety and investigate potential adverse effects, he says. A vaccine able to trigger strong neutralizing antibody responses in clinical tests will still not…

No improvement in death rate for COVID-19 patients who received hydroxychloroquine

Boston, MA — A research team led by investigators from Brigham and Women’s Hospital has evaluated real-world evidence related to outcomes for COVID-19 patients who were treated with hydroxychloroquine or chloroquine analogues (with or without a macrolide). Investigators found no evidence that either drug regimen reduced the death rate among patients. Patients treated with hydroxychloroquine…