A team of researchers led by UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) has found that metformin – a drug commonly used to treat Type 2 diabetes – can successfully reduce symptoms associated with tuberous sclerosis complex (TSC), including reduction in the frequency of seizures and the…
Use of vouchers and coupons offered by pharmaceutical companies to defray patients’ out-of-pocket drug costs is concentrated among a small number of drugs. While these offsets significantly reduce patient costs, they are not targeted to patients who most need the price reduction, according to a study from researchers at the Johns Hopkins Bloomberg School of…
A new study out of the University of Chicago and the University of Illinois Urbana-Champaign in humans, chimpanzees, rhesus macaques and baboons has found key differences in early gene expression in response to pathogen exposure, highlighting the importance of choosing the right animal model for the right questions. The study was published on March 26…
A national survey of parents revealed that most parents who used ride-share services did so with their children, but only half of the respondents reported that children who were 8 years or younger traveled in the recommended child car seats or booster seats when in ride-share vehicles. Among parents of children in this age group,…
CHAPEL HILL, NC – A team led by scientists at the UNC School of Medicine discovered an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems able to exploit this vulnerability. The scientists, whose study is published in Nature Immunology, found that HIV,…
PHOENIX, Ariz. — March 29, 2021 — A review of more than 20 studies by researchers at Arizona State University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggests that nonalcoholic fatty-liver disease (NAFLD) is a growing dietary problem for children across the globe. “The prevalence of fatty-liver disease is…
This week I’ve invited Thorin Klosowski, an editor at Wirecutter, to give us some advice covering our tracks online. Everything you do online — from browsing to shopping to using social networks — is tracked, typically as behavioral or advertising data. But browser extensions are simple, generally free add-ons that you can use to slow…
For them, the half-hour Tyler Perry video that had been playing on repeat on a giant screen in the multipurpose room did not seemed to resonate. Ms. Sandri, who is of Chinese descent, began to understand. “I’m Asian, but I’m not Japanese or Thai or Indian, and they are very different people,” she said. “Until…
Some workplaces encourage employees to donate blood as an act of charity. But six workers at MSCHF, a quirky company based in Brooklyn that’s known for products like toaster-shaped bath bombs and rubber-chicken bongs, offered their blood for a new line of shoes. “‘Sacrificed’ is just a cool word — it was just the MSCHF…
Chris Adams, 36, has spent the past year of the pandemic living with his grandparents in Wichita, Kan., and being “extremely strict” about social distancing. “I never went out,” he said. But starting Monday, when all adults in Kansas become eligible for the coronavirus vaccine, Mr. Adams plans to find a vaccination site where there…