The Cure for Overtourism? Try Viljandi.

Traveling to the interior of a small country that doesn’t see huge numbers of tourists you can usually count on certain things: peace and quiet, pastoral landscapes and maybe a few inquisitive looks. Occasionally, though, you come across a small town that’s especially full of life — without the crowds and traffic of a metropolis.…

Judge John Hodgman on Wedding Traditions

Brandon writes: My fiancée, Ashley, is against wedding traditions like the garter toss and particularly the “cake smash,” where bride and groom smear frosting on each other’s face. But I’m a big fan of these traditions! Please order a cake-smash compromise. The easiest and most just path is to split the difference: Ashley shoves a…

Protein-based vaccine candidate combined with potent adjuvant yields effective SARS-CoV-2 protection

A new protein-based vaccine candidate combined with a potent adjuvant provided effective protection against SARS-CoV-2 when tested in animals, suggesting that the combination could add one more promising COVID-19 vaccine to the list of candidates for human use. The protein antigen, based on the receptor binding domain (RBD) of SARS-CoV-2, was expressed in yeast instead…