The Food and Drug Administration on Friday approved a gene therapy for spinal muscular atrophy, a rare muscle-wasting disease that, in its most severe form, kills many babies before they turn 2. The price will be $2.1 million, believed to be highest ever set for a one-time treatment. The therapy, to be sold as Zolgensma,…
Long before he joined Brooke Geahan at the altar, Brian Nicholson fully understood the meaning of the “in sickness and in health” part of the wedding vows. For most of their courtship, Ms. Geahan was so ill the “in health” portion was in question. The two met in December 2014 at the home of a…
Image CreditJames O’Brien When it comes to discussing climate change, older people may have one advantage: They have watched it happen. In the nine Northeastern states, for instance, where average winter temperatures climbed 3.8 degrees Fahrenheit between 1970 and 2000, they have seen fewer snow-covered days, and more shrubs flowering ever earlier. And they have…
Courtesy of Project Runway Any given episode of Bravo’s Project Runway has no shortage of unique, funky, and always creative outfits. The designs created by the contestants are just half of the appeal, though—the makeup is often a statement in itself. We took three bold looks from the brand-new season of the show and made…
Bette Davis patted him on the butt when she decided he was a good director. Henry Fonda gave him his first books on film theory. Lee Marvin got drunk and told him stories about John Ford’s sadistic side. Vincente Minnelli taught him to be a stickler for detail. Roger Corman advised him to pursue his…
Hi and welcome to Five Weeknight Dishes, food for busy people who still want something good to eat — like pesto, which now that I think of it may be the best thing you can eat. I made a very large batch on Monday to toss with spaghetti, using up mint and parsley that was…
Image From left, Pat Cleveland, Chris Royer, Halston, Alva Chinn and Karen Bjornson in 1980. CreditDustin Pittman There were, it seems, many Halstons. There was the small-town Midwesterner who ascended to the highest levels of fashion, an inspired technician whose bias-cut dresses, masterworks of structure and refined simplicity, altered the look of 20th-century American design. There…
Naomi Scott stars as Princess Jasmine in the new Disney adaption, but her off-duty style is even more magical and has lit up the red carpets. Click through for some of her best looks so far, from her sporty princess look to a chic cerulean pant suit.
A lost sense of taste may refer to a partial or total loss of taste. People may also use this phrase to describe an overpowering and typically unpleasant taste. Many medical issues may lead to a loss of taste. Some of these issues are harmless, while others may require a doctor to diagnose them. The…
Send questions about the office, money, careers and work-life balance to workfriend@nytimes.com. Include your name and location, even if you want them withheld. Letters may be edited. Don’t Let the Boomers Grind You Down I worked for a large corporation for 14 years and found myself stuck and uninspired — logging in only to collect…