Researchers find losartan is not effective in reducing hospitalization from mild COVID-19

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MINNEAPOLIS/ST. PAUL (06/18/2021) — University of Minnesota Medical School researchers determined that the common blood pressure medication, losartan, is not effective in reducing hospitalization for mildly-ill COVID-19 outpatients. In the multicenter, randomized, double-blinded clinical trial, non-hospitalized patients recently diagnosed with COVID-19 were given either losartan or a placebo and monitored for 15 days. The study’s…

Overcoming a newly recognized form of resistance to modern prostate cancer drugs

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IMAGE: Neuroendocrine prostate cancer cells. view more  Credit: Dr. Aaron Udager, Michigan Medicine Cancer cells have an uncanny ability to evolve and adapt to overcome the treatments used against them. While patient survival has been extended by modern drugs that block the production or action of male hormones that fuel prostate cancer — androgen receptor inhibitors…

Will reduction in tau protein protect against Parkinson’s and Lewy body dementias?

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IMAGE: Laura Volpicelli-Daley view more  Credit: UAB BIRMINGHAM, Ala. – Will a reduction in tau protein in brain neurons protect against Parkinson’s disease and Lewy body dementias? A new study, published in the journal eNeuro, suggests the answer is no. If this is borne out, that result differs from Alzheimer’s disease, where reducing endogenous tau levels…

The end of Darwin’s nightmare at Lake Victoria?

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Lake Victoria, which came under the spotlight in 2004 by the documentary “Darwin’s nightmare”, is not only suffering from the introduction and commercialisation of the Nile perch. A study lead researchers from the University of Liège (Belgium) has highlighted other worrying phenomena, particularly climatic ones, which have an equally important impact on the quality of…

New artificial heart shows promising results in ‘auto-mode’ — initial clinical experience reported in ASAIO Journal

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June 18, 2021 – An experimental artificial heart includes an autoregulation control mechanism, or Auto-Mode, that can adjust to the changing needs of patients treated for end-stage heart failure. Outcomes in the first series of patients managed with the new heart replacement pump in Auto-Mode are presented in the ASAIO Journal, official journal of the…

Picky neurons

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IMAGE: The agony of choice: despite being in contact with both eyes, neurons in the mouse visual thalamus only transfer information from one retina. view more  Credit: MPI of Neurobiology / Kuhl The visual thalamus is classically known to relay visual stimuli coming from the retina to the cerebral cortex. Researchers from the Max Planck Institute…

Does cannabis affect brain development in young people with ADHD? Too soon to tell, reports Harvard Review of Psychiatry

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June 18, 2021 – At least so far, the currently limited research base does not establish that cannabis has additional adverse effects on brain development or functioning in adolescents or young adults with attention-deficit/hyperactivity disorder (ADHD), concludes a review in the July/August issue of Harvard Review of Psychiatry. The journal is published in the Lippincott…