ATLANTA – Today, the American College of Rheumatology (ACR) published the 2020 Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases. This is the first, evidence-based, clinical practice guideline related to the management of reproductive health issues for all patients with rheumatic diseases. With 131 recommendations, the guideline offers general precepts that…
All life is challenged by oxidants — reactive molecules or compounds that remove electrons from other molecules — often with adverse effect, commonly referred to as oxidative stress. Consequently, all organisms have evolved specialized antioxidant defenses. In humans and other multicellular animals, that defense depends upon a protein called NRF2 and its inhibitor, KEAP1. In…
Oak Brook, IL – The March edition of SLAS Discovery features the cover article, “CRISPR: A Screener’s Guide,” by Carlos le Sage, Ph.D., Steffen Lawo, Ph.D., and Benedict C.S. Cross, Ph.D., (Horizon Discovery, United Kingdom). In their review, the authors discuss how CRISPR-Cas9 systems are being used widely throughout the drug discovery process and the…
HO CHI MINH CITY, Vietnam — The Arashiyama Bamboo Forest, one of the most visited sites in Kyoto, Japan, was quiet enough to hear the bamboo creaking in the wind. The Ngong Ping 360 cable cars in Hong Kong, which hover over Lantau Island and take passengers to a famous Buddha statue, hung motionless and…
Here’s what you need to know: ImageSpraying disinfectant on Sunday at a market in Daegu, the southeastern city where many of South Korea’s coronavirus infections have been confirmed.Credit…Yonhap, via Agence France-Presse — Getty Images South Korea’s leader urges an ‘all-out, concerted response.’ President Moon Jae-in on Sunday put South Korea on the highest possible alert…
Barbara Smith, a fashion model who created a business empire by catering to the tastes of aspiring black professionals with her restaurants, television shows, bedding and furniture collections and books on entertaining, died on Saturday at her home on Long Island. She was 70. The cause was early-onset Alzheimer’s disease, her family said. Ms. Smith…
Earlier this month, the hard-hit town of Caohe, near the center of the coronavirus outbreak in central China, received an unexpected gift: a large donation from a Taoist nunnery 550 miles away. Another Taoist temple, this one in Caohe itself, contributed tens of thousands of dollars worth of medical equipment to help those sickened by…
In an unexpected move, Prada named Raf Simons as co-creative director joining Miuccia Prada. The powerhouse duo will share “equal responsibilities for creative input and decision-making.” The decision was announced on Sunday at a surprise press conference held on the last day of Milan Fashion Week. Prada joined her family’s namesake label in 1978, premiered…
MILAN — The last days of Milan Fashion Week took place as cases of the coronavirus crept closer and news reports came that at least two people had died in nearby cities. Though there were temperature checks at the airport — a uniformed man with an electronic thermometer greeted people disembarking from London — apparently…
MILAN — In a move that could reshape the fashion world, Miuccia Prada and Patrizio Bertelli, the creative director and chief executive of the Prada Group, the thinking woman’s brand and one of the gravitational poles of the Italian industry, announced on Sunday that they were appointing the Belgian designer Raf Simons as co-creative director…