A new mechanism triggering cell death and inflammation: A left turn that kills
Z-form nucleic acids are double-stranded DNA and RNA molecules with an unusual left-handed double helix structure, as opposed to the classical right-handed Watson-Crick double helix. Z-nucleic acids were discovered more than 40 years ago, but their biological function has remained poorly understood. The group of Professor Manolis Pasparakis at the CECAD Cluster of Excellence in…