Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

IMAGE: Long exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. view more  Credit: SMU DALLAS (SMU) – Researchers at SMU’s Center for Drug Discovery, Design and Delivery (CD4) have succeeded in lab testing the use of chemotherapy with a specific protein inhibitor so that the chemotherapeutic is better absorbed…

Study links sleep-disordered breathing to age acceleration

SAN ANTONIO – Increasing severity of sleep-disordered breathing and sleep disruption are associated with epigenetic age acceleration, according to preliminary results of a new study. Results show that each standard deviation increase in the apnea-hypopnea index, a measure of sleep-disordered breathing severity, was associated with the equivalent of 215 days of biological age acceleration. Similarly,…

Tissue engineering: The big picture on growing small intestines

IMAGE: Fluorescent image of stem cells and progenitor cells. Cells like these can eventually be grown in the laboratory into small intestines to treat babies with severe gastrointestinal challenges. Photo courtesy… view more  Credit: Dr. Grikscheit, Children’s Hospital Los Angeles Babies born prematurely often face intense medical challenges, including intestines that are underdeveloped or diseased. While…