ROCHESTER, Minn. — Difficult-to-treat, chronic wounds in preclinical models healed with normal scar-free skin after treatment with an acellular product discovered at Mayo Clinic. Derived from platelets, the purified exosomal product, known as PEP, was used to deliver healing messages into cells of preclinical animal models of ischemic wounds. The Mayo Clinic research team documented…
The highly infectious SARS-CoV-2 variant that recently emerged in South Africa, known as B.1.351, has scientists wondering how existing COVID-19 vaccines and therapies can be improved to ensure strong protection. Now, researchers reporting in ACS’ Journal of Medicinal Chemistry have used computer modeling to reveal that one of the three mutations that make variant B.1.351…
April 28, 2021 — Using naturalistic driving data and machine learning techniques, researchers at Columbia University Mailman School of Public Health and Columbia’s Fu Foundation School of Engineering and Applied Science have developed highly accurate algorithms for detecting mild cognitive impairment and dementia in older drivers. Naturalistic driving data refer to data captured through in-vehicle…
People of color, those with a higher income and younger individuals are more likely to participate in clinical trials during their cancer treatment according to a new study from the University of Missouri School of Medicine. Clinical trials are research studies that involve people who volunteer to take part in tests of new drugs, current…
Chocolate is a beloved treat, but sometimes the cocoa beans that go into bars and other sweets have unpleasant flavors or scents, making the final products taste bad. Surprisingly, only a few compounds associated with these stinky odors are known. Now, researchers reporting in ACS’ Journal of Agricultural and Food Chemistry have identified the two…
In collaboration with VGP, the research group has published a research paper in Nature on platypus and echidna genomes early this year (see report in the right column). In the Nature current special issue, the research group published another study on the genome of the common marmoset, an important primate model for neurodegenerative diseases, drug…
CORVALLIS, Ore. – Socially just policies aimed at limiting the Earth’s human population hold tremendous potential for advancing equity while simultaneously helping to mitigate the effects of climate change, Oregon State University researchers say. In a paper published this week in Sustainability Science, William Ripple and Christopher Wolf of the OSU College of Forestry also…
A protein variant common in malignant bladder tumor cells may serve as a new avenue for treating bladder cancer. A multi-institution study led by UC Davis Comprehensive Cancer Center researchers found that targeting androgen receptors – a type of protein that is crucial for the function of testosterone – may destroy cancer cells. The study,…
Veterinarians, pet owners and breeders often have preconceived notions about each other, but by investigating these biases, experts at the University of Arizona College of Veterinary Medicine hope to improve both human communication and animal care. “Veterinary medicine may require us to treat the patient, but we are unable to improve pet patient outcomes without…