April 28, 2021 — Using naturalistic driving data and machine learning techniques, researchers at Columbia University Mailman School of Public Health and Columbia’s Fu Foundation School of Engineering and Applied Science have developed highly accurate algorithms for detecting mild cognitive impairment and dementia in older drivers. Naturalistic driving data refer to data captured through in-vehicle recording devices or other technologies in the real-world setting. These data could be processed to measure driving exposure, space and performance in great detail. The findings are published in the journal Geriatrics.
The researchers developed random forests models, a statistical technique widely used in AI for classifying disease status, that performed exceptionally well. “Based on variables derived from the naturalistic driving data and basic demographic characteristics, such as age, sex, race/ethnicity and education level, we could predict mild cognitive impairment and dementia with 88 percent accuracy, “said Sharon Di, associate professor of civil engineering and engineering mechanics at Columbia Engineering and the study’s lead author.
The investigators constructed 29 variables using the naturalistic driving data captured by in-vehicle recording devices from 2977 participants of the Longitudinal Research on Aging Drivers (LongROAD) project, a multisite cohort study sponsored by the AAA Foundation for Traffic Safety. At the time of enrollment, the participants were active drivers aged 65-79 years and had no significant cognitive impairment and degenerative medical conditions. Data used in this study spanned the time period from August 2015 through March 2019.
Among the 2977 participants whose cars were instrumented with the in-vehicle recording devices, 33 were newly diagnosed with mild cognitive impairment and 31 with dementia by April 2019. The researchers trained a series of machine learning models for detecting mild cognitive impairment/dementia and found that the model based on driving variables and demographic characteristics was 88 percent accurate, much better than models based on demographic characteristics only (29 percent) and driving variables only (66 percent). Further analysis revealed that age was most predictive of mild cognitive impairment and dementia, followed by the percentage of trips traveled within 15 miles of home, race/ethnicity, minutes per trip chain (i.e., length of trips starting and ending at home), minutes per trip, and number of hard braking events with deceleration rates ≥ 0.35 g.
“Driving is a complex task involving dynamic cognitive processes and requiring essential cognitive functions and perceptual motor skills. Our study indicates that naturalistic driving behaviors can be used as comprehensive and reliable markers for mild cognitive impairment and dementia,” said Guohua Li, MD, DrPH, professor of epidemiology and anesthesiology at Columbia Mailman School of Public Health and Vagelos College of Physicians and Surgeons, and senior author. “If validated, the algorithms developed in this study could provide a novel, unobtrusive screening tool for early detection and management of mild cognitive impairment and dementia in older drivers.”
###
Co-authors are Carolyn DiGuiseppi, Colorado School of Public Health; David W. Eby and Lisa Molnar, University of Michigan Transportation Research Institute; Linda Hill, University of California San Diego School of Public Health; Thelma J. Mielenz, Columbia Mailman School of Public Health; David Strogatz, Bassett Research Institute; Howard Andrews, Terry Goldberg, Barbara Lang, and Minjae Kim, Columbia Vagelos College of Physicians and Surgeons.
The study was supported by the AAA Foundation for Traffic Safety.
Columbia University Mailman School of Public Health
Founded in 1922, the Columbia University Mailman School of Public Health pursues an agenda of research, education, and service to address the critical and complex public health issues affecting New Yorkers, the nation and the world. The Columbia Mailman School is the seventh largest recipient of NIH grants among schools of public health. Its nearly 300 multi-disciplinary faculty members work in more than 100 countries around the world, addressing such issues as preventing infectious and chronic diseases, environmental health, maternal and child health, health policy, climate change and health, and public health preparedness. It is a leader in public health education with more than 1,300 graduate students from 55 nations pursuing a variety of master’s and doctoral degree programs. The Columbia Mailman School is also home to numerous world-renowned research centers, including ICAP and the Center for Infection and Immunity. For more information, please visit http://www.
Columbia Engineering, based in New York City, is one of the top engineering schools in the U.S. and one of the oldest in the nation. Also known as The Fu Foundation School of Engineering and Applied Science, the School expands knowledge and advances technology through the pioneering research of its more than 220 faculty, while educating undergraduate and graduate students in a collaborative environment to become leaders informed by a firm foundation in engineering. The School’s faculty are at the center of the University’s cross-disciplinary research, contributing to the Data Science Institute, Earth Institute, Zuckerman Mind Brain Behavior Institute, Precision Medicine Initiative, and the Columbia Nano Initiative. Guided by its strategic vision, “Columbia Engineering for Humanity,” the School aims to translate ideas into innovations that foster a sustainable, healthy, secure, connected, and creative humanity.
Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.
