Autophagy is an intracellular degradation process of cytosolic materials and damaged organelles. Researchers at Ubiquitin Project of TMIMS have been studying the molecular mechanism of mitophagy, the selective autophagy process to eliminate damaged mitochondria. PINK1 (a serine/threonine kinase) and Parkin (a ubiquitin ligating enzyme: E3) work together to ubiquitylate the outer membrane proteins of damaged…
Frequently occurring chronic skin inflammation like in atopic dermatitis (AD or neurodermatitis) and psoriasis have different causes such as genetic predisposition, stress or allergens. These frequently occurring skin diseases are mostly attributed by biomedical scientists to a disturbed immune system, although the noticeable thickening and flaking of the epidermis, which is the outermost layer of…
WHO: Giovanni Traverso, MB, BChir, PhD, Associate Physician, Division of Gastroenterology, Brigham and Women’s Hospital; corresponding author of a new article published in JAMA Network Open. Peter Chai, MD, MMS, Assistant Professor, Department of Emergency Medicine, Brigham and Women’s Hospital; first author. WHAT: In the age of COVID-19, mobile robotic telehealth systems could help clinicians…
Beijing, 26 February 2021: the journal Cardiovascular Innovations and Applications (CVIA) has just published the third issue of Volume 5. This issue brings together important research from authors in the USA and China, including several important papers concerned with the various cardiological implications of COVID-19. Papers in the issue are as follows. RESEARCH PAPERS …
Less than one-third of COVID-19 clinical trials are led by women, which is half the proportion observed in non-COVID-19 trials, according to research led by Queen Mary University of London, University of St Andrews, Brigham and Women’s Hospital and Harvard Medical School. The study suggests that gender disparities during the pandemic may signify not only…
Ivermectin, a controversial anti-parasitic drug that has been touted as a potential Covid-19 treatment, does not speed recovery in people with mild cases of the disease, according to a randomized controlled trial published on Thursday in the journal JAMA. Ivermectin is typically used to treat parasitic worms in both people and animals, but scientific evidence…
In North Dakota this week, health officials are sending their first Johnson & Johnson Covid-19 vaccines to pharmacies and urgent care clinics, where people who don’t necessarily have a regular doctor can get the single jab. In Missouri, doses are going to community health centers and rural hospitals. And in North Carolina, health providers are…
A small group of scientists and others who believe the novel coronavirus that spawned the pandemic could have originated from a lab leak or accident is calling for an inquiry independent of the World Health Organization’s team of independent experts sent to China last month. While many scientists involved in researching the origins of the…
Courtesy Of Chloé There are no pants in sight at Gabriela Hearst’s first show for Chloé. The designer, who was announced as creative director in December 2020, heralds the same femininity woven in the house codes of the Parisian atelier, founded by Gaby Aghion in 1952. Hearst’s new reign marks a quiet but remarkable shift…
Within weeks, the world changed, though the extent of the shift would not become clear for months. Mr. Advani recalled a sign posted in the brand’s stores in mid-March that said it would reopen on April 1. “It turned out that April of 2021 would have been ambitious,” he said. At the time, the company…