Genethon, dedicated to designing and developing gene therapy products for rare diseases, received this Monday 30th of November the authorisation from the ANSM, the French National Agency for Medicines and Health Products Safety, to start in France a multicentre international clinical trial for the treatment of Duchenne muscular dystrophy with product GNT 004. This trial’s…
PHILADELPHIA (December 1, 2020) – More than 90 percent of human papillomavirus (HPV)-related cancers could be prevented by widespread uptake of the HPV vaccine. Yet, vaccine use in the United States falls short of public health goals. In an article in JMIR Nursing, researchers explain how they applied user-centered design principles to develop a mobile…
A new analysis from North Carolina State University highlights the realistic pros and cons of apps and other technologies that use artificial intelligence (AI) to benefit older adults, including those facing dementia and cognitive decline. The work focuses on how these technologies can help older adults preserve their autonomy, and addresses ethical concerns that have…
Millions of sperm enter the race to fertilize, but only one wins the sprint to the egg. Now Yale researchers have discovered that these winning sperm possess a few key molecular characteristics that differentiate them from those left behind, they report Dec. 1 in the journal eLife. Sperm tails are lined with channels containing pores…
Dana-Farber Cancer Institute researchers will present more than 40 research studies at the virtual 62nd American Society of Hematology (ASH) Annual Meeting on December 5-8, including two studies that were selected for inclusion in the official press program. Dana-Farber is home to one of the largest and most respected treatment centers for patients with disorders…
Immunotherapies have transformed the landscape of cancer treatment by allowing physicians to alter or augment patients’ immune response to better attack malignant tumors. But some tumors — known as “cold tumors” — fly under the immune system’s radar. Checkpoint inhibitors, which are the basis of many immunotherapies, don’t work well against them. A team of…
Boston — Though childbirth is often anticipated with optimism and enthusiasm, approximately 10 to 20 percent of pregnant individuals also experience mental health challenges during the weeks immediately before and after birth. Depression, anxiety and trauma-related disorders can all be exacerbated by increased stress related to pregnancy and postpartum experiences. But it’s unknown how the…
NEW YORK, NY (Dec. 1, 2020)–Researchers within the Observational Health Data Services and Informatics (OHDSI) community were recently awarded a $10 million contract from the U.S. Food and Drug Administration (FDA) to provide support to the Biologics Effectiveness and Safety (BEST) program, which was launched by the FDA Center for Biologics Evaluation and Research (CBER)…
If there is a silver lining in cancer’s chaotic biology, it’s that the same traits that give cancer cells a growth advantage often present opportunities for sabotaging them. That’s the central idea behind a new research paper published November 23 in Proceedings of the National Academy of Sciences (PNAS) by Xuejun Jiang, a cell biologist…
A Rutgers study has discovered that vitamin D regulates calcium in a section of the intestine that previously was thought not to have played a key role. The findings have important implications on how bowel disease, including ulcerative colitis and Crohn’s disease, may disrupt calcium regulation. In a healthy person, the body absorbs calcium to…