Publication: Journal of General Internal Medicine Authors: Girish Nadkarni, MD, Co-Chair; Anuradha Lala, MD, Member; Benjamin Glicksberg, PhD, Member; and other coauthors of the Mount Sinai COVID Informatics Center at the Icahn School of Medicine at Mount Sinai. Bottom Line: This study describes characteristics of patients with COVID-19 who returned to the ER or required…
Cynthia Lum, Professor and Director, Center for Evidence-Based Crime Policy, Criminology, Law and Society, and Christopher Koper, Principal Fellow and Associate Professor, Center for Evidence-Based Crime Policy, Criminology, Law and Society, are conducting analyses to help the Fairfax County Police Department prepare, prevent, and respond to ongoing challenges posed by COVID-19. As part of this…
When news about a novel coronavirus switched from a chronicle of its progress in China to headlines about a worldwide COVID-19 pandemic, Gladstone Institutes scientist Nadia Roan, PhD, was in the midst of publishing several papers on T cells and their role in HIV spread and long-lasting infections. Aside from serving as HIV targets and…
Scientists have developed an injectable drug that blocks HIV from entering cells. They say the new drug potentially offers long-lasting protection from the infection with fewer side effects. The drug, which was tested in non-human primates, could eventually replace or supplement components of combination drug “cocktail” therapies currently used to prevent or treat the virus.…
The word ‘synbiotic’ appears on a growing number of food and supplement products, with synbiotic ingredients showing promise for modulating the community of microbes living in the human gut, while providing a health benefit. Synbiotics are generally understood to be a combination of a probiotic and a prebiotic–but experts have deemed this description too limiting…
BOSTON – A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan. The international team’s novel bioluminescent repair reporter (BLRR)-based system can be used to monitor DNA repair pathways directly in animals as well as…
A new study of 27 patients hospitalized with COVID-19 has provided a detailed map of natural killer (NK) cell responses to SARS-CoV-2 infection, revealing that specific characteristics of NK cell activation associate with different levels of disease severity. The findings are consistent with previous reports that NK cells exist in lower frequencies in the blood…
Programmable DNA nanoswitches that bind to viral RNA in human body fluids may provide an inexpensive platform to rapidly detect a wide variety of emerging viruses, including SARS-CoV-2, according to a new study. This approach may make testing more manageable in resource-limited areas, since it does not require enzymes or significant laboratory infrastructure, only costs…
Boston – A new study shows that nephrologists do not always agree on their interpretation of images from urine sediment tests, which are frequently ordered to evaluate a variety of kidney diseases. Led by researchers at Boston Medical Center and published in JAMA Network Open, the findings indicate the need to standardize education and training…
BEER-SHEVA, Israel, August 21, 2020 – A new peer-reviewed study published in Science Advances confirms the success of a new COVID-19 pooling test that identifies all positive subjects, including asymptomatic carriers, in a single round of testing. P-BEST, an algorithmic method for pooling-based efficient SARS-CoV-2 testing, was developed by a group of researchers from Ben-Gurion…