checkmate 743 shows that dual immunotherapy, nivolumab + ipilimumab

Denver–(Embargoed for 7 a.m. EST August 8, 2020) The combination of first-line nivolumab and ipilimumab demonstrated an improvement of overall survival for patients with unresectable malignant pleural mesothelioma compared to platinum-based chemotherapy, according to research presented today at the International Association for the Study of Lung Cancer Virtual Presidential Symposium. The study is presented by…

Phase 3 eXalt3 study shows significantly longer progression-free survival

Denver–(Embargoed for 7 a.m. EST August 8, 2020)–Patients with non-small cell lung cancer (NSCLC) carrying anaplastic lymphoma kinase (ALK) gene alterations who received ensartinib experienced substantially longer progression-free survival than a matched group of patients who received crizotinib, according to a presentation at the International Association for the Study of Lung Cancer World Conference on…

Addition of sintilimab to pemetrexed and platinum improved progression-free survival

Denver–(Embargoed for 7 a.m. EST August 8, 2020)–The interim analysis of ORIENT-11, a phase III double-blind randomized trial has shown a nearly two-fold increase in progression-free survival with addition of sintilimab to chemotherapy in patients with advanced or metastatic non-squamous non-small cell lung cancer without EGFR or ALK genomic aberrations, according to research data presented…