When it comes to traumatic injuries, it’s a race against time. A person with major hemorrhage can die from blood loss within minutes, so staunching the wound and getting them to a hospital as fast as possible is critical. Bleeding from the extremities can be slowed with compression but what about internal bleeding? In a…
Marcel Leist, Professor of In-Vitro Toxicology and Biomedicine at the University of Konstanz, and Thomas Hartung, Professor of Environmental Health Sciences at the University of Konstanz and Doerenkamp-Zbinden Chair of Evidence-Based Toxicology at Johns Hopkins Bloomberg School of Public Health in Baltimore, have been awarded the Ursula M. Händel Animal Welfare Prize 2020 of the…
This research defines the new mini-invasive technique for the treatment of osteoid osteomas, which are benign but painful bone-forming tumors that usually involve long bones, with 10-20% of the cases having localization at the spine. The most common symptom in osteoid osteomas is back pain which is generally responding to nonsteroidal anti-inflammatory drugs, but in…
Philadelphia, July 31, 2020–Continuous glucose monitoring (CGM) tracks glucose levels of people with type I or type II diabetes through a device that monitors levels throughout the day. These devices improve control of blood sugar levels by alerting patients when their levels go too high or low, but patients need to use the technology consistently…
DETROIT – Diabetes, obesity and nonalcoholic fatty liver disease (NAFLD) are all common diseases that can lead to serious health implications. NAFLD affects over 30% of Americans, and is characterized as a fatty liver, which can progress to an inflammatory and fibrotic liver, called nonalcoholic steatohepatitis (NASH), as well as liver cirrhosis. The molecular causes…
Grants totaling nearly $3.5 million give early career investigators independence to pursue brave and bold cancer research. Fifteen scientists from across the country were named Damon Runyon Fellows. The recipients of this prestigious, four-year award are outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators. The Fellowship encourages…
Epilepsy is a wide-spread neurological disorder that affects around 50 million people worldwide. It is characterized by recurrent epileptic seizures, which are sudden bursts of electrical activity in the brain. There are many different types of seizures, and a person with epilepsy can experience more than one type. Clinicians today use EEG measurements, with electrodes…
When we say someone has a quick mind, it may be in part thanks to our expanded cerebellum that distinguishes human brains from those of macaque monkeys, for example. Sometimes referred to by its Latin translation as the ‘”little brain”‘, the cerebellum is located close to the brainstem and sits under the cortex in the…
Scientists have found that countries with mandatory Bacillus Calmette-Guérin (BCG) vaccination until at least the year 2000 tended to exhibit slower infection and death rates during the first 30 days of the outbreak of COVID-19 in their country. By applying a statistical model based on their findings, the researchers further estimated that only 468 people…
By screening potential monoclonal antibody (mAb)-based drugs solely based on a measure of their colloidal stability, scientists may be able to weed out mAbs that do not respond efficiently in solution early in the drug discovery process, according to a new study. This finding could enable researchers to overcome a major hurdle to drug development…