EMA qualification opinion on cellular therapy module of the EBMT Registry

The European Society for Blood and Marrow Transplantation (EBMT) registry has been qualified by EMA as a suitable platform for the collection of data for post-authorisation safety surveillance studies. The registry is now considered suitable to perform pharmacoepidemiological studies for regulatory purposes, concerning Chimeric Antigen Receptor (CAR) T-cell therapy used in the treatment of haematological…

Considerably reduced toxicant levels in heated tobacco prototype compared to cigarettes

Bristol, February 28th 2019 – New research* suggests that toxicants of notable public health interest are substantially reduced in the aerosol from our heated tobacco product (HTP) prototype, compared to smoke from a standard reference cigarette. HTPs generate a nicotine-containing aerosol with a tobacco taste through the heating of tobacco via an electrical device. The…

Embryos’ signaling proteins go with the flow

IMAGE: Rice University graduate student Joseph Massey sets up an experiment to study the WNT signaling pathway in developing cell lines. The pathway plays a central role in cell differentiation as… view more  Credit: Jeff Fitlow/Rice University HOUSTON – (March 1, 2019) – How cells in developing embryos communicate depends a great deal on context, according…

How hair dye works (video)

IMAGE: Whether you need a disguise to run from the law or are just trying to emulate *NSYNC-era frosted tips, you may need some chemical assistance to put the hue in… view more  Credit: The American Chemical Society WASHINGTON, March 1, 2019 — Whether you need a disguise to run from the law or are just…

Tracking firefighters in burning buildings

IMAGE: McMaster University researchers, working with colleagues from other institutions led the development of a self-powered, fireproof sensor to track the movements of firefighters and others who work beyond the line… view more  Credit: McMaster University HAMILTON, March 1, 2019 – McMaster researchers, working with partners at other universities, have created a motion-powered, fireproof sensor that…