Researchers find febrile infants may not need painful tests, antibiotics, hospitalizations

(SACRAMENTO, Calif.) – A national research team led by UC Davis Health clinicians and researchers from the University of Michigan, Nationwide Children’s Hospital and Columbia University, has derived and validated a new protocol for emergency departments that can determine which infant patients with fevers, age 60 days or younger, are at low risk of significant…

Hormone therapy may increase cardiovascular risk during gender transition

DALLAS, February 18, 2019 — Patients receiving hormone therapy as part of their gender-transition treatment had an elevated risk for cardiovascular events, including strokes, heart attacks and blood clots, according to a study published in the American Heart Association’s journal Circulation. The results are based on analysis of medical records of 3,875 Dutch individuals who…

Physicists pinpoint a simple mechanism that makes bacteria resistant to antibiotics

IMAGE: These are researchers Maikel Rheinstädter and Adree Khondker of McMaster University. view more  Credit: JD Howell, McMaster University Physicists at McMaster University have for the first time identified a simple mechanism used by potentially deadly bacteria to fend off antibiotics, a discovery which is providing new insights into how germs adapt and behave at a…

Small cell lung cancer may respond to combination of immunotherapy and DNA damage repair inhibitors

IMAGE: Lauren Averett Byers, M.D. view more  Credit: MD Anderson Cancer Center Researchers at The University of Texas MD Anderson Cancer Center have discovered that a combination of immune checkpoint blockade and targeted therapies that block normal DNA damage repair (DDR) achieved significant tumor regression in mouse models of small cell lung cancer (SCLC), suggesting a…

Depression reversed in male mice by activating gene that helps excite neurons

IMAGE: This is Dr. Xin-Yun Lu, molecular behavioral neuroscientist at the Medical College of Georgia at Augusta University. view more  Credit: Phil Jones, Augusta University Senior Photographer AUGUSTA, Ga. (Feb. 18, 2019) – Directly activating a gene important to exciting our excitatory neurons and associated with major depression may help turn around classic symptoms like social…