Not all cancerous tumors are created equal. Some tumors, known as “hot” tumors, show signs of inflammation, which means they are infiltrated with T cells working to fight the cancer. Those tumors are easier to treat, as immunotherapy drugs can then amp up the immune response. “Cold” tumors, on the other hand, have no T-cell…
Researchers have found that a natural molecule can effectively block the binding of a subset of human antibodies to SARS-CoV-2. The discovery may help explain why some COVID-19 patients can become severely ill despite having high levels of antibodies against the virus. In their research, published in Science Advances today (22 April 2021), teams from…
Researchers have identified another potential target for neutralizing antibodies on the SARS-CoV-2 Spike protein that is masked by metabolites in the blood. As a result of this masking, the target may be inaccessible to antibodies, because they must compete with metabolite molecules to bind to the otherwise open region, the study authors speculate. This competitive…
The University of Minnesota is one of two institutions in the United States to host a new center established by the Biostasis Research Institute (BRI) aimed at creating human organ banks through the cryogenic storage of organs donated for transplantation. BRI is launching and funding the Organ and Tissue Preservation Center at the U of…
In a worldwide study of 2,100 pregnant women, those who contracted COVID-19 during pregnancy were 20 times more likely to die than those who did not contract the virus. UW Medicine and University of Oxford doctors led this first-of-its-kind study, published today in JAMA Pediatrics. The investigation involved more than 100 researchers and pregnant women…
As he sat at his computer on a recent Sunday afternoon preparing for the workweek ahead, Jonathan Frostick, a program manager at an investment bank in London, said he could not breathe. His chest tightened and his ears started to pop. He was having a heart attack. His first thoughts were of how this would…
But later that year, the Newtons moved to Monte Carlo to avoid France’s high taxes. They spent their winters at the Chateau Marmont hotel in Los Angeles. In the mid-’90s, when the hotelier André Balazs bought the then-seedy Chateau and reimagined it as a playground of old Hollywood and contemporary fashion, the Newtons were its…
In an early analysis of coronavirus vaccine safety data, researchers at the Centers for Disease Control and Prevention have found no evidence that the Pfizer-BioNTech or Moderna vaccines pose serious risks during pregnancy. The findings are preliminary and cover just the first 11 weeks of the U.S. vaccination program. But the study, which included self-reported…
MADRID — Mariano Puig, who helped transform his family-owned Spanish perfume maker into an international fashion house that encompasses the brands Paco Rabanne, Nina Ricci, Carolina Herrera and Jean Paul Gaultier, died on April 13 in Barcelona. He was 93. Puig, the company that bears the family name, confirmed the death. As a member of…
Crocheted blankets. Hand-sewn masks. Wonky ceramics, chemical-free soaps and colorful beadwork. In a year filled with uncertainty, grief and isolation, many of us turned to crafting — whether we had any skill in it or not. Did you pick up a new hobby? Or perfect an old one? Were the finished products meant as gifts?…