Body’s natural pain killers can be enhanced

Fentanyl, oxycodone, morphine–these substances are familiar to many as a source of both pain relief and the cause of a painful epidemic of addiction and death. Scientists have attempted for years to balance the potent pain-relieving properties of opioids with their numerous negative side effects–with mostly mixed results. Work by John Traynor, Ph.D., and Andrew…

Targeting drug-resistant breast cancer with estrogen

LEBANON, NH – Researchers at Dartmouth’s and Dartmouth-Hitchcock’s Norris Cotton Cancer Center (NCCC) hope to make estrogen therapy a more accessible treatment option for breast cancer patients who could benefit from it. Anti-estrogen treatments, which block growth signals from estrogen receptors (ER) in tumors, are effective treatments for ER+ breast cancer. But it is common…

How oxygen radicals protect against cancer

FRANKFURT. Originally, oxygen radicals – reactive oxygen species, or ROS for short – were considered to be exclusively harmful in the body. They are produced, for example, by smoking or UV radiation. Because of their high reactivity, they can damage many important molecules in cells, including the hereditary molecule DNA. As a result, there is…

Mount Sinai study finds that blood clotting drug commonly used for orthopedic surgeries does not increase complications for high-risk patients

Paper Title: Safety of Tranexamic Acid in Hip and Knee Arthroplasty in High-risk Patients Journal: Anesthesiology Authors: Jashvant Poeran MD, PhD, Director of the Center for Clinical and Outcomes Research, and Associate Professor of Population Health Science & Policy and Orthopedics at the Icahn School of Medicine at Mount Sinai; Calin S. Moucha, MD, Chief…

Wolters Kluwer and Chinese Medical Association to publish new open access journals Cardiology Discovery and Infectious Diseases & Immunity

April 23, 2021 – Wolters Kluwer, Health announced today the publication of two new, fully open access journals under its LippincottĀ® portfolio as part of an ongoing collaboration with the Chinese Medical Association (CMA). Cardiology Discovery and Infectious Diseases & Immunity will accelerate the dissemination, exchange, and utilization of scientific research results in their respective…