An international team of researchers led by Baylor College of Medicine and Houston Methodist has discovered a strategy that can potentially address a major challenge to the current treatment for choroidal neovascularization (CNV), an aggressive form of age-related macular degeneration, the leading cause of irreversible blindness in the elderly. Anti-vascular endothelial growth factor (anti-VEGF)…
OAK BROOK, Ill. (July 16, 2020) – Racial/ethnic minority patients admitted to the hospital with COVID-19 infection are more likely to have more severe disease on chest X-rays than white/non-Hispanic patients, increasing the likelihood of adverse outcomes, such as intubation or death, according to a study published in the journal Radiology. Emerging data show that…
OAK BROOK, Ill. (July 16, 2020) – COVID-19 is associated with life-threatening blood clots in the arteries of the legs, according to a study published in Radiology. Researchers said COVID-19 patients with symptoms of inadequate blood supply to the lower extremities tend to have larger clots and a significantly higher rate of amputation and death…
In order to survive within the remote and harsh anatomical microenvironments of the central nervous system, the disseminated cancer cells that cause rare yet deadly leptomeningeal metastases (LM) hijack crucial iron micronutrients from native macrophages, researchers report. The work highlights the remarkable plasticity of tumor cells and reveals potential new avenues for treating these particularly…
A recently discovered hypercompact CRISPR enzyme found only in huge bacteriophages, and known as CRISPR-CasΦ, is functional, a new study by Patrick Pausch, Jennifer Doudna and colleagues reports, and it provides a powerful new tool in the CRISPR genome editing toolbox, including because it can target a wider range of genetic sequences compared to Cas9…
The increased severity and mortality of SARS-CoV-2 infections in older individuals may be related to inflammageing – an age-associated phenomenon of increased general inflammation. In this Perspective, Arne Akbar and Derek Gilroy discuss this possibility as well as strategies to mitigate related effects. Inflammageing is thought to be caused, at least partially, by deterioration of…
Welcome. How are you? Wednesdays were a bear even before the pandemic came to town and made most days feel like Wednesdays. Now Wednesdays are like Wednesdays squared, like Nebraska on a cross-country drive, 456 miles from Omaha in the East all the way to the Wyoming line. They’re a long way from a weekend…
Wading into the contentious debate over reopening schools, an influential committee of scientists and educators on Wednesday recommended that, wherever possible, younger children and those with special needs should attend school in person. Their report — issued by the prestigious National Academies of Science, Engineering and Medicine, which advises the nation on issues related to…
One of the joys of working from home is being able to make myself something for lunch that no one else in my family even remotely likes. No matter if it’s stuffed with garlicky bread crumbs, spiced grains, ground meat, canned fish, beans or cheese, there’s something about the soft texture of a baked tomato…
We have seen the future of European fashion, and it is California. Peering out from behind the curtain of a long lockdown, designers in Paris and Milan seemed unanticipatedly hopeful during the digital shows this past week. It was not so much that they were willing to forgo the inimitable theater of the fashion show…