Phase 2 randomised controlled trial of a recombinant adenovirus type-5-vectored COVID-19 vaccine (Ad5-vectored COVID-19 vaccine) was conducted in China in April 2020 and involved more than 500 people The primary objective of the study was to evaluate the immune response and safety of the vaccine, and to determine the most suitable dose for a phase…
PROVIDENCE, R.I. [Brown University] — Which sleep stage is most important for learning: REM or non-REM? Does sleep improve learning by enhancing skills while people snooze, or by cementing those skills in the brain so that they’re less likely to forget them? Do these processes occur every time someone sleeps, or only after they have…
Boston, Mass. – In the early days of the COVID-19 pandemic, the disease was characterized by many as a flu-like respiratory infection mainly affecting the lungs. Now, physicians recognize that the coronavirus can impact organs throughout the body. In a collaboration among physicians at Beth Israel Deaconess Medical Center (BIDMC) and Columbia University Irving Medical…
A replicating RNA vaccine, formulated with a lipid-based nanoparticle emulsion that goes by the acronym LION, produces antibodies against the COVID-19 coronavirus in mice and primates with a single immunization. These antibodies potently neutralize the virus. The effects occurred within two weeks after administration through injection into a muscle. The level of antibodies generated was…