A protein that helps trap bacteria may contribute to metastasis in breast cancer

PHILADELPHIA – The protein peptidyl arginine deiminase 4 (PAD4), which enables some immune cells to trap bacteria, promoted breast cancer metastasis in mice when expressed in cancer cells, according to data published in Molecular Cancer Research, a journal of the American Association for Cancer Research. “Breast cancer is a leading cause of cancer-related death among…

New research shows promise to treat female group A streptococcus genital tract infections

Philadelphia, March 19, 2020 – Puerperal sepsis, also known as childbed fever, is the leading cause of maternal deaths. In this novel study in The American Journal of Pathology, published by Elsevier, scientists report on the discovery of group A streptococcus (GAS) surface proteins involved in female reproductive tract infections such as puerperal sepsis that…