The Lancet: Preliminary results from Russian trials find that vaccine candidates led to no serious adverse events and elicit antibody response

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The new paper reports the findings of two open-label, non-randomised phase 1/2 trials looking at a frozen formulation and a freeze-dried formulation of a two-part vaccine. The two-part vaccine included two adenovirus vectors – recombinant human adenovirus type 26 (rAd26-S) and recombinant human adenovirus type 5 (rAd5-S) In the phase 1 part of each trial,…

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Autophagy: the beginning of the end

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Autophagosomes first form as cup-shaped membranes in the cell, which then grow to engulf the cellular material designated for destruction. The formation of these membranes is catalyzed by a complex machinery of proteins. “We have a very good knowledge of the factors involved in autophagosomes formation”, explains group leader Sascha Martens, “but how they come…

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The case of ibuprofen: evidence of huge impact of COVID-19 misinformation when coming from credible sources

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In March, in the early days of the coronavirus pandemic in Europe, a tweet from the French Health Minister, Olivier Verán, advised patients with COVID-19 not to take ibuprofen, an anti-inflammatory drug with analgesic and antipyretic properties. He even warned that taking it would increase mortality among COVID-19 patients, even though the statement was not…

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Identification and treatment key in responding to COVID-19 health anxiety in children

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Early identification and treatment is vital to avoid long-term mental health consequences from COVID-19 among children and young people, say researchers. Writing in the Behavioural and Cognitive Psychotherapy Journal, the psychologists from the University of Bath highlight how health anxieties can be triggered by changes like returning to school and argue that young people need…

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Mason researchers to provide bioinformatic analysis

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Virginia Espina, Research Associate Professor, Applied Proteomics and Molecular Medicine, received $21,000 from Baylor Research Institute for a project in which Mason researchers are providing biostatistics and bioinformatic analysis for integrating multi-omic data sets from a breast cancer cohort. Specimens are from patients with triple-negative breast tumors. Data analysis will include correlations between proteomic, metabolomic,…

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New peer reviews of COVID-19 preprints from the MIT Press journal RAPID REVIEWS COVID-19

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CAMBRIDGE, MA – September 2, 2020–Rapid Reviews: COVID-19 (RR:C19), is an open-access overlay journal published by the MIT Press that accelerates peer review of COVID-19-related research preprints to advance new and important findings and prevent the dissemination of false or misleading scientific news. For the month of August, the preprints selected for review covered a…

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Historical case studies on pandemics

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Whether it’s the plague, cholera or currently COVID-19: epidemics are part of human history. Long before there were vaccinations or microscopes for the investigation of pathogens, societies had to develop coping strategies. These are described in the brochure “Distant Times so Close: Pandemics and Crises reloaded”, which is the first in a series of historical-archaeological…

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2020 Virtual National Health Research Forum

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Day One (All times East Coast Time) Day 1 September 8, 2020 11 a.m. Welcome and Opening Remarks Mary Woolley, President & CEO, Research!America Elections 2020 Speaker: Steve Clemons, Editor-At-Large, The Hill 11:50 a.m. Panel: Securing a Science-Strong Future Moderator: Victor Dzau, MD, President, National Academy of Medicine Panelists: Valerie Conn, President, Science Philanthropy…

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