Announcing a new article publication for BIO Integration journal. In this review article the authors Yingxue Deng, Rui Huang, Songyin Huang and Menghua Xiong from South China University of Technology, Guangzhou, Guangdong, P. R. China and Sun Yat-sen University, Guangzhou, Guangdong, P. R. China discuss how nanoparticles enable efficient delivery of antimicrobial peptides for the treatment of deep infections.
Antimicrobial peptides (AMPs) are rarely directly used to treat deep infections due to their systemic toxicity and low bioavailability. The authors summarize recent progress that researchers employed nanoparticles based delivery systems to deliver AMPs for the treatment of deep infections.
Nanoparticles-based delivery systems offer a strategy to increase the therapeutic index of AMPs by preventing proteolysis, increasing the accumulation at infection sites, and reducing toxicity. Especially, the development of intelligent nanocarriers can achieve selective activation and active target in the infectious sites, thus improving the therapeutic efficacy against bacterial infection and reducing the toxicity against normal tissues.
###
Article reference: Yingxue Deng, Rui Huang, Songyin Huang and Menghua Xiong, Nanoparticles Enable Efficient Delivery of Antimicrobial Peptides for the Treatment of Deep Infections. BIO Integration, 2021, https:/
BIO Integration is fully open access journal which will allow for the rapid dissemination of multidisciplinary views driving the progress of modern medicine.
As part of its mandate to help bring interesting work and knowledge from around the world to a wider audience, BIOI will actively support authors through open access publishing and through waiving author fees in its first years. Also, publication support for authors whose first language is not English will be offered in areas such as manuscript development, English language editing and artwork assistance.
BIOI is now open for submissions; articles can be submitted online at:
https:/
Please visit http://www.
Editorial Board: https:/
Please visit http://www.
Editorial Board: https:/
BIOI is available on the IngentaConnect platform (https:/
Submissions may be made using ScholarOne (https:/
There are no author submission or article processing fees.
Follow BIOI on Twitter @JournalBio; Facebook (https:/
ISSN 2712-0074
eISSN 2712-0082
Keywords: Antimicrobial peptides, deep infections, drug delivery, nanoparticles.
Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.
