PEPTIC trial comparing strategies to prevent stress ulcers in ICU patients needing mechanical ventilation

What The Study Did: Researchers report on a randomized clinical trial that compared two strategies (proton pump inhibitors vs. histamine-2 receptor blockers) to prevent stress ulcers among adult patients in intensive care units who needed mechanical ventilation. The trial was conducted at 50 ICUs in five countries to compare in-hospital death rates using the two strategies. The…

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Green in tooth and claw

Go ahead, take a big bite. Hard plant foods may have made up a larger part of early human ancestors’ diet than currently presumed, according to a new experimental study of modern tooth enamel from Washington University in St. Louis. Scientists often look at microscopic damage to teeth to infer what an animal was eating.…

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Long-term risks cast further doubt on the use of Viagra for fetal therapy

University of Manchester scientists investigating a possible treatment for foetal growth restriction (FGR), a condition in which babies grow poorly in the womb, have urged further caution on the use of Viagra. The drug, commonly used to treat erectile dysfunction, as it enhances blood flow — has been undergoing trials as a potential treatment for…

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Study quashes controversial vitamin C treatment for sepsis with global trial

In 2017 a paper was published asserting that intravenous vitamin C given to patients with sepsis was literally a life saver. Despite the study only looking at 47 subjects the results garnered international coverage and was adopted in many ICUs worldwide. The global burden of sepsis is estimated at up to 19 million cases annually…

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Internet use reduces study skills in university students

Research conducted at Swansea University and the University of Milan has shown that students who use digital technology excessively are less motivated to engage with their studies, and are more anxious about tests. This effect was made worse by the increased feelings of loneliness that use of digital technology produced. Two hundred and eighty-five university…

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Doubling down on cancer-causing genes

RIVERSIDE, Calif. — One way to tackle cancer, the second-leading cause of death in the United States, is to target oncogenes — genes that have the potential to cause cancer. The University of California, Riverside, has received a $2.2 million grant from the National Cancer Institute of the National Institutes of Health that will help…

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Transformational innovation needed to reach global forest restoration goals

The U.N. and other international organizations agree that forest restoration is a critical part of the collective global effort to combat climate change, reduce extinctions, and improve the lives of people in rural communities. Dozens of nations have pledged to restore 230 million hectares of forest so far as part of projects such as the…

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Rich rewards: Scientists reveal ADHD medication’s effect on the brain

Attention-deficit hyperactivity disorder (ADHD) is a neurobiological disorder characterized by symptoms of hyperactivity, inattention and impulsivity. People with the condition are often prescribed a stimulant drug called methylphenidate, which treats these symptoms. However, scientists do not fully understand how the drug works. Now, researchers at the Okinawa Institute of Science and Technology Graduate University (OIST)…

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Psychedelic drugs could help treat PTSD

Clinical trials suggest treatment that involves psychedelics can be more effective than psychotherapy alone. More than three million people in the United States are diagnosed each year with post-traumatic stress disorder, whose symptoms include nightmares or unwanted memories of trauma, heightened reactions, anxieties, and depression—and can last months, or even years. People with PTSD—difficulty recovering…

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Violence and adversity in early life can alter the brain

Childhood adversity is a significant problem in the US, particularly for children growing up in poverty. Those who experience poverty have a much higher risk of being exposed to violence and suffering from a lack of social support, which can have long-term consequences including higher rates of diabetes, cancer, and other diseases. People exposed to…

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