New candidate cancer genes identified using math models

(Boston)—Computational modeling is the use of computers to simulate and study the behavior of complex systems. Computational approaches are widely adopted in the bioimedical sciences and can be used to sift through large volumes of complex data to extract recurrent patterns that may point to a disease’s causes and effects. Researchers from Boston University School…

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Pulmonary arterial hypertension targeted for new treatment by Sheffield scientists

Scientists at the University of Sheffield have identified an antibody that has the ability to stop and reverse the progression of pulmonary arterial hypertension Pulmonary arterial hypertension is a rare but fatal disease which is only currently cured by lung transplantation These research findings will now be prioritised for the development of a new drug…

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EurekAlert! fellowship spotlights early-career science journalists from Latin America, other emerging regions

Five early-career science journalists from emerging regions will attend the 2020 AAAS Annual Meeting as winners of the 2020 EurekAlert! Fellowships for International Science Reporters. The winners will receive financial support to travel to Seattle, Wash., where the world’s largest multidisciplinary scientific meeting will take place Feb. 13-16. Fellowship applications were accepted from China,…

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Uninfected individuals born to mothers living with HIV at risk of obesity and asthma

BOSTON — Adolescents and young adults who were born to mothers with HIV but remained uninfected themselves still face a greatly heightened risk of obesity and asthma-like symptoms, researchers from Massachusetts General Hospital (MGH) have found. In a study published in Journal of Acquired Immune Deficiency Syndromes (JAIDS), the team revealed for the first time…

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New finding offers possibility for preventing age-related metabolic disease

New Haven, Conn. — A study by researchers at Yale has uncovered why belly fat surrounding organs increases as people age, a finding that could offer new treatment possibilities for improving metabolic health, thereby reducing the likelihood for diseases like diabetes and atherosclerosis that stem from inflammation. Led by Dr. Vishwa Deep Dixit, the Waldemar…

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Yale study provides insights into how fibrosis progresses in the human lung

New Haven, Conn. — A Yale-led collaborative study boosts scientific understanding of how the lung disease idiopathic pulmonary fibrosis (IPF) progresses, providing a roadmap for researchers to discover new treatment targets for the disease. The study, led by Naftali Kaminski, M.D., the Boehringer-Ingelheim Endowed Professor of Internal Medicine and chief of the Section of Pulmonary,…

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Dr. Wayne Bardin, 85, Innovative Researcher on Birth Control, Dies

Dr. C. Wayne Bardin, a groundbreaking researcher in reproductive physiology, who was instrumental in the development of long-acting contraceptive methods — like Norplant, Jadelle and Mirena — used by millions of women around the world, died on Oct. 10 at his home in Manhattan. He was 85. His wife, Beatrice Bardin, confirmed the death without…

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Don’t Call Tara Subkoff an ‘It’ Girl

Dan Flavin’s outsize light sculpture looked like a luminous frame. Not one to miss an opportunity, Tara Subkoff posed strategically in front of it, its rectangular shape and pastel fluorescence complementing the candied pink of her Simone Rocha dress. “There’s an optimism to this piece,” Ms. Subkoff said. That suited her. “I’m the kind of…

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