Betrayed by bile: bile acids help norovirus sneak into cells

A new study led by researchers at Baylor College of Medicine and published in the Proceedings of the National Academy of Sciences reveals that human noroviruses, the leading viral cause of foodborne illness and acute diarrhea around the world, infect cells of the small intestine by piggybacking on a normal cellular process called endocytosis that…

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Making blood on demand: How far have we come?

The reconstitution of the blood system in humans holds great therapeutic potential to treat many disorders, like blood cancers, sickle-cell anemia and others. Successful reconstitution requires the transplantation and engraftment of hematopoietic (or blood) stem cells (HSCs), which after reaching their niche, start producing all types of blood cells, including platelets, white and red blood…

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F.D.A. Failed to Ensure Safe Prescribing of Opioids, Documents Show

WASHINGTON — Newly unearthed documents show that the Food and Drug Administration failed to use its policing powers to make sure a program to curb improper prescribing of opioids was effective, researchers say. The lax oversight, they point out, occurred as the epidemic was growing and tens of thousands of people were dying from overdoses…

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Opioid Deaths Rise When Auto Plants Close, Study Shows

The last two decades have brought both a sharp decline in automaking jobs in the United States and the rise of a deadly epidemic of opioid abuse. According to a new study, the two trends may well be related. The study, published Monday in JAMA Internal Medicine, found that opioid deaths were about 85 percent…

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A Cookbook You’ll Turn to Again and Again

With its homespun snapshots, “The Corn Exchange Cookbook” is not exactly a lavish gift book, but its pages promise to become stained and dog-eared from frequent use. MJ Adams — a New York chef who worked with Tom Valenti, David Page and Edna Lewis — moved to Rapid City, S.D., in 1996 after a family…

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Alinea Had a Hand in This Coffee Liqueur

Rhine Hall is a fruit brandy distiller in Fulton Market district of Chicago. The company, the outgrowth of a backyard hobby, now makes more than a dozen brandies and similar products. About a year ago, it teamed up with Alinea, the Michelin three-star restaurant in Chicago, to create a coffee liqueur. Made from handpicked beans…

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New Jersey, Now Known for Rice

California and South Carolina are the usual sources for American-grown rice, but you can add New Jersey to the list. In Pennington, southwest of New Brunswick, Blue Moon Acres is cultivating assorted rices. There are medium- and long-grain brown rice; white sushi rice; a mix of short-grain brown and black rice, called black and tan,…

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Add This Cheese to Your Party Board

Many more sheep than humans live on the windswept Croatian island of Pag in the Adriatic Sea. The sheep, a breed called paska ovka, graze on the landscape, and their milk takes on the briny tang of the environment in a local cheese called Paski Sir. This fairly firm-textured cheese, with a nutty aroma and…

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A King Cake With a Raspberry Twist

This year Judith Norell, an owner of Silver Moon Bakery on the Upper West Side, has added a new twist, raspberry preserves, to her galette des rois, or king cake, the confection served for Epiphany on Jan. 6. It’s usually fashioned from puff pastry and filled with marzipan, with a good luck token hidden inside.…

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