University of Kentucky launches clinical trial to evaluate new COVID-19 treatments

Clinical leaders from the University of Kentucky’s Markey Cancer Center, College of Medicine and College of Pharmacy have launched a clinical trial for experimental therapies to treat patients infected with COVID-19. The trial will investigate the effectiveness of azithromycin, ivermectin and camostat mesylate—drugs that could inhibit replication of SARS-CoV-2, the virus that causes the disease.…

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Use of a homozygous G608G progeria mouse model for degenerative joint diseases research

BOSTON — Hutchinson-Gilford Progeria Syndrome (HGPS) is a fatal condition that is especially prevalent in the skin, cardiovascular and the musculoskeletal systems. There exists a wide gap between existing knowledge of the disease and a potential treatment or cure. In a study published today in the journal Proceedings of the National Academies of Science, researchers…

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Neural logic

Everything we do comes down to a series of neural signals that translate into physical behaviors. We receive information through our senses, sensory neurons convert this information into electrical and chemical signals that are processed by other neurons in our brains and ultimately, motor neurons fire muscles that move our limbs. But how these signals…

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Effects of antioxidant rich Indo-Mediterranean foods on pre-heart failure

The role of diets in the pathogenesis of cardiac dysfunction is controversial. However, it is well known that Western diet causes oxidative stress and has pro-inflammatory effects, whereas Mediterranean style diets are anti-inflammatory. Recently, cohort studies and case control studies, have demonstrated that western style diets rich in sugar and physical inactivity with obesity are…

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Leading the way in innovative research for COVID-19 patients

CLEVELAND — As the COVID-19 pandemic continues, there is great interest in studying treatment and prevention approaches for the disease. Cleveland Clinic is participating in a number of research projects related to COVID-19. As an international leader in biomedical research, Cleveland Clinic has formed a multidisciplinary clinical trials committee to evaluate therapies for mild to…

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Early mammography screening lowers risk of developing fatal breast cancer

An analysis of more than half a million women in Sweden reveals that mammography screening reduces the rates of advanced and fatal breast cancers. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society (ACS). For the analysis, László Tabár, MD, of Falun Central Hospital, Sweden, Stephen Duffy, MSc,…

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Study finds rising rate of mental health visits among youth to emergency departments

(COLUMBUS, Ohio) — While the number of pediatric emergency department (ED) visits across the nation has remained stable over the last 10 years, visits for mental health disorders have risen 60% and the rate of visits for deliberate self-harm have increased 329%. In a study published today in Pediatrics, Nationwide Children’s Hospital researchers looked at…

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Research shows even animals benefit from social distance to prevent disease

MAY 11, 2020 — Microorganisms living inside and on our body play a crucial role in both the maintenance of our health and the development of disease. Now researchers at UTSA have uncovered evidence about the importance of maintaining physical distance to minimize the spread of microbes among individuals. The scientists observed monkeys in the…

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