Fine-tuning adoptive cell therapy for advanced cancers

Adoptive cell transfer immunotherapy is one of the most promising new treatments for people with hard-to-treat cancers. However, the process is complex and needs fine-tuning in order to develop more treatment strategies that will work for more people. In a new study looking at adoptive cell transfer products bearing a transgenic T-cell receptor (TCR), researchers…

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Antibiotics disrupt development of the ‘social brain’ in mice

Antibiotic treatment in early life impedes brain signalling pathways that function in social behaviour and pain regulation in mice, a new study by Dr Katerina Johnson and Dr Philip Burnet has found. It was published today in BMC Neuroscience. Katerina Johnson, from the University’s Departments of Psychiatry and Experimental Psychology, was researching the effects of…

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Popular hypertension drugs don’t increase risk of COVID-19 severity, fatality

CHICAGO — A new Northwestern Medicine study in mice found a widely used class of drugs to treat patients with hypertension, cardiovascular disease and diabetic kidney disease — many of whom are elderly — does not increase the risk of developing a severe and potentially fatal COVID-19 infection, as previously feared. There have been concerns…

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Getting under the skin of psoriasis

Psoriasis, a chronic skin condition that causes itchy, red, scaly patches, afflicts more than 8 million Americans and 125 million people worldwide. Small molecule-based drugs like steroids can penetrate the skin to treat the condition, but they can cause skin irritation and thinning and their efficacy can decrease over time. Antibodies that target specific inflammation-related…

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Georgia State faculty get COVID-19 funding to develop coronavirus test tools

ATLANTA—Georgia State University researchers have received a one-year, $200,000 rapid response grant from the National Science Foundation to develop a tool to detect the presence of SARS-CoV-2, the virus causing the COVID-19 pandemic. Technology being developed by chemistry professor Gangli Wang in collaboration with assistant biology professor Mukesh Kumar is anticipated to provide several benefits,…

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Tapestry C.E.O. Jide Zeitlin Resigns After Misconduct Allegation

Jide Zeitlin, the chief executive of Tapestry and one of only four Black chief executives in the Fortune 500, resigned on Tuesday and later said the unexpected move, less than a year into his tenure, was related to a past relationship. The company’s board had been made aware of a misconduct allegation involving Mr. Zeitlin…

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A Plan to Revive Gotham Bar and Grill

Gotham Bar and Grill, in business for 36 years and one of New York’s best-known restaurants, closed in March at the start of the pandemic lockdown. At the time, management said the situation was untenable, and that the closing was permanent. Now it seems there is a possibility that Gotham could reopen after all, if…

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Worried About Crowded Flights? Know Where Your Airline Stands

As air travel has ticked up in the last month, airlines have divided into two camps: those blocking strategic seats to offer more space, and those willing to fill planes to capacity. In the latter camp, United Airlines never instituted limits and continues to sell all available seats as demand allows. As of July 1,…

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