The Key to a Perfect Italian-American Sauce

Pimientos is what they’re called in dictionaries, in seed catalogs. But in Brooklyn, they’re known as cherry peppers, just as they are in most places where Italian-Americans gather and eat. Small and pumpkin-shaped, like miniature bell peppers, they can be found in deli cases stuffed with cubes of provolone and wisps of prosciutto, on antipasto…

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Deciphering the equations of life

Research led by the University of Arizona has resulted in a set of equations that describes and predicts commonalities across life despite its enormous diversity. «Our study develops a general theory to study the extraordinary diversity of life using simple rules common to all species. We can further apply these rules to predict specific traits…

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Tropical flower offers potential new route for treating pancreatic cancer

An international team of scientists led by the University of Bath have made drug-like molecules inspired by a chemical found in a tropical flower, that they hope could in the future help to treat deadly pancreatic cancer. Pancreatic cancer is one of the most aggressive and deadly cancers Around 10,000 patients in the UK per…

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BU finds concerns about other painkillers contributed to opioid crisis

Patients with chronic pain caught between cardiovascular concerns about non-opioid analgesics and addiction risks of opioids, likely causing significant unmet need for pain relief. A new Boston University School of Public Health (BUSPH) study published in JAMA Network Open shows that the decline in prescriptions of non-opioid analgesics—largely NSAIDs and COX-2 inhibitors—in the early 2000s…

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Study supports long-term benefits of non-drug therapies for pain

A new study based on Veterans Affairs health records finds that non-drug therapies given to military service members with chronic pain may reduce the risk of long-term adverse outcomes, such as alcohol and drug disorder and self-induced injuries, including suicide attempts. The findings appeared online Oct. 28, 2019, in the Journal of General Internal Medicine.…

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Mechanisms help pancreatic cancer cells avert starvation

A new study reveals the mechanism that helps pancreatic cancer cells avoid starvation within dense tumors by hijacking a process that pulls nutrients in from their surroundings. Led by researchers at NYU Grossman School of Medicine, the study explains how changes in the gene RAS — known to encourage the abnormal growth seen in 90…

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Increasing transparency in the healthcare sector: More might not be better

INFORMS Journal Operations Research New Study Key Takeaways: Increasing quality transparency in the short-term typically improves social welfare and reduces inequality among patients. Increasing transparency in the long-term can decrease social welfare and increase inequality. The best solution is to target public reporting to specific patient populations and incentivize hospitals. CATONSVILLE, MD, December 11, 2019…

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Hyperactive FOXA1 reprograms endocrine-resistant breast cancer to become metastatic

A team led by researchers at Baylor College of Medicine and Harvard Medical School has unveiled a novel mechanism that helps explain how endocrine-resistant breast cancer acquires metastatic behavior, opening the possibility of new therapeutic strategies. Published in the Proceedings of the National Academy of Sciences, the study shows that hyperactive FOXA1 signaling, which previously…

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Training the brain: resilience program helps student-athletes adjust to college life

Imagine the impact on first-year college student-athletes in highly competitive programs if you could teach them resilience — if they learned skills to cope with high expectations, challenging academic courses, rigorous training and physical injuries, homesickness and even the stressors of life beyond college. In newly published research, a unique and expanding program at the…

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