Perspective: T cell responses to COVID-19 are a crucial target for research

While early research on the adaptive immune response to COVID-19 primarily looked at antibodies, more information is now emerging on how T cells react to the SARS-CoV-2 virus — addressing a crucial knowledge gap, say Daniel Altmann and Rosemary Boyton in a new Perspective. While antibody responses are generally much easier to study, T cells…

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Close-up of SARS-CoV-2 protein shows how it interferes with host anti-viral immunity

A detailed study of a SARS-Cov-2 protein, Nsp1, with a central role in weakening the host anti-viral immune response shows that it effectively shuts down production ofproteins in the host. Although SARS-Cov-2 features additional inhibitors of host innate immune defenses, targeting the interaction of this protein, Nsp1, with the host may be an important therapeutic…

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Coordination helps avoid continental COVID-19 resurgence, European modeling study shows

Coordinated lockdown strategies among countries is key to preventing resurgent COVID-19 outbreaks in continental Europe, a new modeling study shows. A continental epidemic could occur as many as five weeks earlier when well-connected countries with stringent existing interventions end their interventions prematurely, the study’s authors say. As rates of new COVID-19 cases begin to decline…

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Extending Cruise Ban, C.D.C. Says Ships Helped Spread Coronavirus

As the coronavirus pandemic raged around the world, cruise ship companies continued to allow their crews to attend social gatherings, work out at gyms and share buffet-style meals, violating basic protocols designed to stop the spread of the highly transmissible virus, the Centers for Disease Control and Prevention said in a scathing 20-page order, released…

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CVS Fined for Prescription Errors and Poor Staffing at Pharmacies

In a rare public rebuke of the nation’s largest retail pharmacy chain, state regulators in Oklahoma cited and fined CVS for conditions found at four of its pharmacies, including inadequate staffing and errors made in filling prescriptions. While the fine of $125,000 on Wednesday was small for CVS Health — it paid its chief executive…

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What We Eat During a Plague

AT THE OUTSET of “The Decameron,” the 14th-century story collection by the Italian writer Giovanni Boccaccio, a group of 10 young nobles — seven women and three men — flee “the death-dealing pestilence” sweeping through Florence and make their way to a country repast in the Tuscan hills. “Using very temperately of the most delicate viands…

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Washington Redskins Fans Collected Memorabilia for Years. What Now?

Matt Pearson was born in Washington, D.C., in 1983, which means he is old enough to remember watching his hometown football team win their second Super Bowl in 1988. He remembers the smell of chips and beer, his parents screaming like crazy at the television, the team’s record-breaking comeback and victory. After that, said Mr.…

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Taylor Lorenz on Reporting, Teens and Internet Culture

We spend a lot of our days chatting with each other about things we see online, trying to make sense of it all. This week in the Styles newsletter, Wait …, Taylor Lorenz, a Styles reporter, Lindsey Underwood, a Styles editor, and Jessica Grose, the Parenting editor, discussed how we report on teenagers and the…

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Hillary Gregg, Line Cook at Top-Shelf Restaurants, Dies at 73

This obituary is part of a series about people who have died in the coronavirus pandemic. Read about others here. Hillary Gregg signed on in 1979 as a line cook at the celebrated Quilted Giraffe, which was to restaurants what Studio 54 was to nightclubs — chock-a-block with celebrities and influential business, media and political…

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In Coronavirus Vaccine Race, China Strays From the Official Paths

The offer to employees at the state-owned oil giant was compelling: Be among the first in China to take a coronavirus vaccine. The employees at PetroChina could use one of two vaccines “for emergency use” to protect themselves when working overseas as part of China’s ambitious infrastructure program, according to a copy of the notice,…

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