A new mechanism triggering cell death and inflammation: A left turn that kills

Z-form nucleic acids are double-stranded DNA and RNA molecules with an unusual left-handed double helix structure, as opposed to the classical right-handed Watson-Crick double helix. Z-nucleic acids were discovered more than 40 years ago, but their biological function has remained poorly understood. The group of Professor Manolis Pasparakis at the CECAD Cluster of Excellence in…

Details

New UC Davis research suggests parents should limit screen media for preschoolers

New research from University of California, Davis, suggests that parents should delay introducing their children to any screen media, as well as limit preschool-age children’s use of mobile devices, including smartphones and tablets. The research was published in the Journal of the American Medical Association Pediatrics this week. Over a two-and-a-half-year period, researchers assessed 56…

Details

Purdue innovators moving to fast-track COVID-19 diagnostic, therapeutic solutions

WEST LAFAYETTE, Ind. — As the coronavirus pandemic spreads across the U.S. and the world, Purdue University scientists are working to move solutions to diagnose and treat the virus to the marketplace as soon as possible. The Purdue Research Foundation Office of Technology Commercialization is working with innovators from across the university to patent and…

Details

A COVID-19 palliative care pandemic plan: An essential tool

OTTAWA — Palliative care physicians have created a coronavirus disease 2019 (COVID-19) palliative care plan as an essential tool to provide care and help manage scare resources during the pandemic. The plan, which focuses on 8 critical elements — «stuff,» «staff,» «space,» «systems,» «sedation,» «separation,» «communication» and «equity» — is published in CMAJ (Canadian Medical…

Details

Scientists modify CAR-T cells to target multiple sites on leukemia cells

LOS ANGELES (March 31, 2020) — In a new pre-clinical study published this week in the journal Leukemia, the research team of Children’s Hospital Los Angeles investigator Hisham Abdel-Azim, MD, MS, worked with colleagues to engineer T-cells to identify and target multiple sites on acute lymphoblastic leukemia cells instead of just one. The early collaboration…

Details

BIDMC physician-scientists spearhead effort to address COVID-19 testing swab shortage

Boston, Mass. — As the numbers of patients with confirmed and suspected COVID-19 in the United States continue to rise exponentially, physician-researchers at Beth Israel Deaconess Medical Center (BIDMC), part of Beth Israel Lahey Health, launched a collaborative and open-source effort to address the shortage of swabs that is hampering the nation’s ability to test…

Details

The Human Stories of the Coronavirus Pandemic

Welcome to Lives, where we are continually updating with ways the world is adapting to a pandemic. What good timing for it to be National Doctor’s Day. Perhaps you didn’t think to observe it last year. This year, as the coronavirus pandemic has sickened nearly 800,000 worldwide, people are wholeheartedly making sure they thank a…

Details

How to Donate N95 Masks

“Giving a mask to a health care provider on the front line has more potential for a positive impact than wearing it around the grocery store,” says Conrad Amenta, director of policy and strategic initiatives at the California Academy of Family Physicians, which represents some 11,000 family doctors. Many of them have recently said they…

Details