Immunotherapy kicks and kills HIV by exploiting a common virus

IMAGE: MDC1 (blue) signaling to T helper cells (yellow) that harbor latent HIV. view more  Credit: Donna Stolz, Ph.D./University of Pittsburgh, Center for Biologic Imaging PITTSBURGH, April 3, 2019 — In a first on the quest to cure HIV, University of Pittsburgh Graduate School of Public Health scientists report today in EBioMedicine that they’ve developed an…

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Is adenosine the missing link in restless leg syndrome?

IMAGE: Journal of Caffeine and Adenosine Research is the first and only journal dedicated to the rapidly advancing field of caffeine and adenosine signaling research. view more  Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, April 3, 2019-Researchers have identified a common mechanism implicating adenosine in the cause of restless leg syndrome (RLS) symptoms —…

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Secure relationship with new parents reduces anxiety in adopted children

Philadelphia, April 2, 2019 — In children who have experienced early institutional care, a strong relationship with their adoptive parents plays a positive role in brain development and the child’s long-term mental health, according to a new study, published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier. Childhood is a time when parents…

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Tipping the scales

IMAGE: The researchers equipped a cellular protein (gray) with a modified lysine amino acid building block (pink), to which the bacterial enzyme sortase (yellow) transmits a ubiquitin molecule (blue). view more  Credit: K. Lang / TUM Human cells have a sophisticated regulatory system at their disposal: labeling proteins with the small molecule ubiquitin. In a first,…

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More policy work needed to reduce use of smokeless tobacco, say researchers

Researchers at the University of York have shown that regulations on smokeless tobacco are still lacking, despite 181 countries agreeing to a common approach to controlling the demand and supply. The study, published in The Lancet Oncology, highlighted that of the 181 countries using the WHO Framework Convention on Tobacco Control (FCTC), only 138 define…

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The brain’s auto-complete function

IMAGE: Participants first saw images of scenes together with one of two objects. Later they only saw the scene images and were asked to remember which object was associated with the… view more  Credit: © Cognitive and Clinical Neurophysiology Group/Uni Bonn When looking at a picture of a sunny day at the beach, we can almost…

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Abnormalities in a protein affecting how nerve cells change shape

IMAGE: This is image shows human HD neurons in green in a culture differentiated from patient HD iPSCs (induced pluripotent cells). Increased levels of Rac1 activity were measured in HD neuronal… view more  Credit: CHDI, Inc. and Dake Family Fund. Amsterdam, NL, April 3, 2019 — Since 1993, when the gene that causes Huntington’s disease (HD)…

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New campaign encourages organ and tissue donation to advance medical research

IMAGE: Human tissue poster. view more  Credit: Janine McCarthy, M.P.H. & Kristie Sullivan, M.P.H. WASHINGTON—The Physicians Committee for Responsible Medicine—a nonprofit with more than 175,000 members including doctors, scientists, and laypeople—has launched a new effort today to encourage people to become organ and tissue donors to help scientists save human lives and reduce and replace animal…

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