Predicting side effects

A multi-institutional group of researchers led by Harvard Medical School and the Novartis Institutes for BioMedical Research has created an open-source machine learning tool that identifies proteins associated with drug side effects. The work, published June 18 in the Lancet journal EBioMedicine, offers a new method for developing safer medicines by identifying potential adverse reactions…

Details

Research news tip sheet: Story ideas from Johns Hopkins Medicine

Medical Cannabis Consumers Use Less Healthcare Resources and Report Better Quality Of Life Media Contact: Vanessa McMains, Ph.D. Although more than 2 million people are registered in state medical cannabis programs across the United States, very little is known about the medical benefits of cannabis. What knowledge has been gained is from programs approved by…

Details

Less sleep reduces positive feelings

Sleeping less than normal impacts how we feel the next morning. «Not in the sense that we have more negative feelings, like being down or depressed. But participants in our study experienced a flattening of emotions when they slept less than normal. They felt less joy, enthusiasm, attention and fulfilment,» says Associate Professor Ingvild Saksvik-Lehouillier…

Details

No disadvantages to having kids early

When some species are heavily hunted, animal mortality increases and they have fewer offspring in the course of their lives. To compensate for this, animals that are hunted often respond by becoming sexually mature and bearing young earlier than species that are not hunted. In other words, animals being hunted have a «faster» life history.…

Details

Women and men still choose partners like they used to

Women seem to care more about security, whereas good looks matter more to men. It used to be that way, and it still is in most places, regardless of the major social changes that have occurred over time. Women often prefer men older than themselves, and men often want younger women. When the wishes of…

Details

DFG establishes interdisciplinary commission for pandemic research

Against the background of the current coronavirus pandemic, the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is to establish an interdisciplinary commission for pandemic research. The commission will be made up of 18 members representing all research disciplines, and its task will be to strengthen the knowledge-driven research which is essential to pandemic and epidemic research…

Details

Mutations linked to intellectual disability point to overly active ion channe

Two mutations identified in individuals with developmental and epileptic brain disease can be traced back to the same ion channel. Researchers have now elucidated how both independent mutations affect the channel’s function: by making it overly active and highly sensitive to stimulation. The findings are an important step towards unraveling what causes the patients’ symptoms.…

Details

COVID-19 may have consequences for mental health

The global COVID-19 pandemic has affected the physical lives of most people. But now there are also indications that the pandemic has negative consequences for the mental health of the people being infected, the healthcare professionals and the population as a whole. This is shown in a new Danish review of 43 scientific articles that…

Details

Nanoparticle for overcoming leukemia treatment resistance

UConn associate professor of pharmaceutics Xiuling Lu, along with professor of chemistry Rajeswari M. Kasi, was part of a team that recently published a paper in Nature Cell Biology finding a commonly used chemotherapy drug may be repurposed as a treatment for resurgent or chemotherapy-resistant leukemia. One of the largest problems with cancer treatment is…

Details