Check In: Hotel Review: Modern Luxury in the Vineyards of France

There is no shortage of landmarks and charming chateaus in two of France’s greatest wine regions, the Loire Valley and Champagne. Modern, design-focused lodging, however, has been much slower to develop. But two recently opened properties in the region — one a renovation, the other a new development — are changing that. RELAIS DE CHAMBORD…

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Medical News Today: Major depression: Existing drug reduces symptoms by 45 percent

For the first time in decades, researchers have identifed a new medication that can successfully treat major depression. An existing oral drug may relieve major depression. Depression affects about 300 million people across the globe, making the condition the «leading cause of ill health and disability worldwide,» according to the World Health Organization (WHO). In…

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At P.S.G., a Style Few Clubs Can Match

PARIS — A few days before Paris St.-Germain traveled to Liverpool in September to begin its latest quest to win the Champions League, Dani Alves and Kylian Mbappé stood on a stage in a starkly lit room in the basement of the Parc des Princes. In front of them, a crowd of dozens of journalists,…

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Mickey Turns 90, and the Disney Marketing Machine Celebrates

LOS ANGELES — A two-hour prime-time special on ABC. Cupcakes the size of cars at Disneyland Paris. Collaborations with a dozen fashion designers, including Marc Jacobs. More than 30 books, including one from Taschen so big it comes with a carrying handle. Small and subtle are not the Walt Disney Company’s style. But a new…

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Resy Acquires Reserve, in the Fierce Tussle Over Restaurant Reservations

Resy, the restaurant-reservation service founded in 2014, said Friday that it had acquired its smaller competitor Reserve. Though Resy is the nation’s largest privately held reservation service, it is still small in comparison with OpenTable, which was bought by the publicly traded Priceline Group (now called Booking Holdings) in 2014 for $2.6 billion and is…

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Poor Disaster Oversight Imperiled Nursing Homes, Senate Report Finds

A Senate inquiry faulted state and federal oversight for fatal heat strokes and chaotic evacuations at nursing homes after last year’s hurricanes, calling for tougher disaster preparedness standards on Friday. Officials with the Centers for Medicare and Medicaid Services, a federal agency that was a subject of the inquiry, have said they would clarify expectations…

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Where ‘Yes! To Affordable Groceries’ Really Means No to a Soda Tax

SEATTLE — Standing in a supermarket produce aisle, her face shadowed with dread, the middle-aged woman speaks directly to the camera and makes a plea for common decency. “We should not be taxed on what we eat,” she says in a commercial that is being broadcast across Washington State. “We need to eat to survive,…

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Pharrell for Chanel Is Coming to a Store Near You

Pharrell Williams has a lot on his plate right now—from opening his Miami eatery Swan and Bar Bevy (a partnership wit nightlife tycoon David Grutman) to making sure Donald Trump never plays «Happy» at another one of his rallies again. But even in the midst of all this, Pharrell isn’t too busy to lend his…

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F.D.A. Approves Powerful New Opioid Despite Warnings of Likely Abuse

WASHINGTON — The Food and Drug Administration on Friday approved a new form of an extremely potent opioid to manage acute pain in adults, weeks after the chairman of the advisory committee that reviewed it asked the agency to reject it on grounds that it would likely be abused. The drug, Dsuvia, is a tablet…

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Know Your Squash: How They Look, How They Cook

As Thanksgiving gatherings go, they are a motley group: the Curcurbitaceae, a vine-growing family with nearly 1,000 members, including pumpkins, melons, zucchini and cucumbers. Some are gourds — hard-shelled, bitter, stringy and suitable only for decoration. But the winter squashes offer countless delicious uses in soups, salads, main courses, side dishes, breads and desserts. Their…

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