Biomarker may predict if immunotherapy is right choice for colorectal cancer patients

DUARTE, Calif. — Foundational research by a City of Hope physician-scientist and his colleagues could one day help metastatic colorectal cancer patients decide whether to choose immunotherapy or chemotherapy as their first treatment option. «Immunotherapy is the new, hot thing, but sometimes traditional chemotherapy can be a better choice,» said Marwan Fakih, M.D., senior author…

Details

Researchers find gene for urethral obstruction

IMAGE: Caroline Kolvenbach, Dr. med. Alina Hilger, Prof. Dr. rer. nat. Benjamin Odermatt and Dr. med. Gabriel Dworschak. view more  Credit: © Photo: Volker Lannert/Uni Bonn Even before birth, an obstructed urethra can cause a variety of issues in the unborn child, ranging from mild urinary problems to kidney failure. This highly variable disease is called…

Details

New chemical probe for visualizing brain immune cells

IMAGE: Age-dependent microglia labelling by CDr20. Three different aged mice (P180, P360 and P660) from wild-type or triple-transgenic mouse model of Alzheimer’s disease (3xTg-AD) mice were intravenously injected with CDr20. The… view more  Credit: The Je Lab. Dr. Masahiro Fukuda. Duke-NUS Intravital Imaging Core. Researchers in South Korea and Singapore have, for the first time, developed…

Details

Chemical modifiers tag-team to regulate essential mechanism of life

SAN FRANCISCO, CA—May 2, 2019— Scientists at the Gladstone Institutes have made a key observation about one of the most fundamental biological processes: gene transcription. A gene’s job is to provide a cell with the instructions to create a specific protein. The first step of this process is called transcription, during which the DNA is…

Details

Up Next: Patti Harrison Bucks Transgender Stereotypes, One Joke at a Time

Name: Patti Harrison Age: 28 Hometown: Orient, Ohio Now lives: In a two-bedroom house in the Echo Park neighborhood of Los Angeles that she shares with a roommate. Claim to fame: Ms. Harrison is an actress, comedy writer and screwball performer who doesn’t take her rising profile in Hollywood too seriously. She appeared in a…

Details

There Are New Options in Trans Underwear

Image Carmen Liu’s first lingerie fashion show in London.CreditAna Cuba for The New York Times On a recent Thursday in London, a group of models strutted down the catwalk to “Woman’s World,” by Cher, donning matching lacy thong and bra sets, which they tastefully accented with silky robes. They were all trans women, and the…

Details

Medical News Today: Pain at big toe joint: Everything you need to know

People may experience pain at the big toe joint as a result of many common problems, including arthritis, injuries, and bunions. The pain can make everyday activities, including walking, more challenging. The metatarsophalangeal (MTP) joint attaches the big toe to the foot. This joint is vital for supporting the body and allowing the toe to…

Details