NRG oncology trial of metformin for non-small cell lung cancer

Initial results of NRG-LU001 indicate that, although the diabetes agent metformin was well-tolerated by patients, the agent has not clearly improved progression-free survival (PFS) or overall survival (OS) for trial participants with locally advanced non-small cell lung cancer (NSCLC). These results are based on local center reported outcomes. Trial participants will continue to be followed…

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NRG trial suggests total neoadjuvant therapy for locally advanced rectal cancer is safe

Results from the first experimental arm using veliparib as part of total neoadjuvant therapy (induction chemotherapy followed by chemoradiotherapy and surgery; TNT) in patients with locally advanced rectal adenocarcinoma on the NRG Oncology Phase II clinical trial NRG-GI002 were recently presented at the American Society of Clinical Oncology (ASCO) Annual Meeting. Results were reported on…

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In-situ measurement of 3D protein structure inside living eukaryotic cells

IMAGE: Target proteins are expressed inside sf9 cells, then measured using «in-cell » NMR spectroscopy. Unique statistical analysis with the help of Bayesian inference is applied to calculate the accurate 3D structure… view more  Credit: Tokyo Metropolitan University Tokyo, Japan — Researchers from Tokyo Metropolitan University have successfully determined the high-resolution three-dimensional structure of proteins inside…

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LaSalle Leffall Jr., 89, Dies; Cancer Society’s First Black Leader

Dr. LaSalle D. Leffall Jr., a surgeon and educator who as the first black president of the American Cancer Society was a leader in promoting awareness of the risks of cancer, particularly among African-Americans, died on May 25 in Washington. He was 89. His son, LaSalle Leffall III, said Dr. Leffall himself died of cancer…

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North Carolina to Investigate After Concerns Raised at Children’s Hospital

North Carolina’s secretary of health on Friday called for an investigation into a hospital where doctors had suspected children with complex heart conditions had been dying at higher than expected rates after undergoing heart surgery. Dr. Mandy Cohen, the secretary, said in a statement that a team from the state’s division of health service regulation…

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‘Screen Time’ Is Over

The debate over screen time is typically accompanied by a good deal of finger-wagging: The digital experience is a ruinous habit, akin to binge-eating curly fries, gambling on cock fights or drinking whiskey with breakfast. Meanwhile, social scientists who are trying to study the actual psychological effects of screen time are left in a bind.…

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Rent Here and Eat Well

When Frankie Celenza is home, hungry and doesn’t feel like cooking, relief can be found an elevator and an escalator ride away. A faster-than-Grubhub trip lands him inside DeKalb Market Hall, a mix of sandwich shops and noodle joints that’s essentially in the basement of City Tower, Mr. Celenza’s Downtown Brooklyn rental building. Yes, it…

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The 21 Best Sneaker Brands For the Gym, Commuting, And Everything Else You Like to Do

Whether you’re an athlete, gym junkie, frequent commuter, or «sneakerhead,» one thing everyone can agree on is that sneakers are an essential part to life. Dramatic? Maybe, but sneakers provide breathable comfort, versatility, and durability that you wouldn’t normally get from towering pumps or too-flat shoes. Serena Williams wore a pair of bedazzled kicks to…

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Yoga’s Instagram Provocateur

Image Alex Auder at her yoga studio in Philadelphia. Asked by the photographer to do a yoga pose, she declined. “I hate yoga,” she said.CreditMark Makela for The New York Times You cannot swing a cat (pose) on Instagram without hitting photographs of yoga instructors with perfect figures twisted into perfect shapes, selling essential oils…

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Medical News Today: What causes heartburn and nausea?

Heartburn and nausea are both common gastrointestinal complaints, which means they have to do with the digestive system. Heartburn is also called gastroesophageal reflux. It has nothing to do with the heart. Rather, it occurs when acid from the stomach flows backward into the esophagus — the tube that connects the throat to the stomach.…

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