Lawsuits Lay Bare Sackler Family’s Role in Opioid Crisis

The Sacklers had a new plan. It was 2014, and the company the family had controlled for two generations, Purdue Pharma, had been hit with years of investigations and lawsuits over its marketing of the highly addictive opioid painkiller OxyContin, at one point pleading guilty to a federal felony and paying more than $600 million…

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Medical News Today: Weight loss: How the ‘love hormone’ might help

A new study has investigated oxytocin’s effects on the brain regions that help control eating behavior to explore the possibility of using this hormone as a treatment for obesity. Researchers get to grips with how oxytocin alters our brain’s response to food. Oxytocin is a hormone that plays an essential role in social interaction, trust,…

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New therapy targets cause of adult-onset muscular dystrophy

IMAGE: Scripps Research graduate student Angel Angelbello and chemistry professor Matthew D. Disney, PhD, report promising data about their RNA-binding myotonic dystrophy type 1 compound in PNAS. view more  Credit: Scripps Research JUPITER, Fla. — April 1, 2019 — People diagnosed with myotonic dystrophy type 1 have difficulty unclenching muscles due to a genetic defect that…

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A bald gene find­ing

IMAGE: Scottish Deerhound have coarse, longish hair, but every now and then there are hairless individuals in litters. view more  Hairlessness in dogs can be the result of deliberate breeding or, in certain breeds, a defect. A recent study completed at the University of Helsinki describes a gene variant in the SGK3 gene, which causes hairlessness…

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GGC launches EpiSign, a novel clinical test for epigenetic changes

IMAGE: EpiSign uses an Illumina Infinium Methylation EPIC bead chip array to analyze DNA methylation at hundreds of thousands of loci across the genome. view more  (GREENWOOD, SC) April 1, 2019 — Greenwood Diagnostic Laboratories at the Greenwood Genetic Center, in collaboration with London Health Sciences Centre (LHSC), announce the launch of a new diagnostic test…

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Martin Borch Jensen to present at the 6th Aging Research for Drug Discovery Forum in Basel

IMAGE: Martin Borch Jensen, Co-Founder and CSO of Gordian Biotechnology, to present ‘Bringing aging biology into drug development at the 6th Aging Research for Drug Discovery Forum in Basel, Switzerland. view more  Credit: Insilico Medicine Monday, April 1, 2019 — Today Insilico Medicine, a biotechnology company developing the end-to-end drug discovery pipeline utilizing the next generation…

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Counties with more trees and shrubs spend less on Medicare, study finds

IMAGE: The study found that increases in forest and shrub cover corresponded to decreases in health care spending. No such relationship was found with other types of vegetative land cover, however. view more  Credit: Graphic by Gopikrishna J. Pillai, Scientific Illustrator CHAMPAIGN, Ill. — A new study finds that Medicare costs tend to be lower in…

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Study estimates how common carriers of polyglutamine disease-associated gene variants are in general population

Bottom Line: Huntington disease is one of nine rare hereditary neurodegenerative diseases known as polyglutamine diseases. This observational study estimated how common carriers with intermediate and pathological ranges of polyglutamine disease-associated gene variants were among the general population using data from five European studies that included DNA samples for more than 14,000 participants without a…

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Is conception by IVF associated with childhood cancer risk?

Bottom Line: This study compared the risk of childhood cancer diagnosed in the first decade of life among children conceived by in vitro fertilization with those children conceived naturally. Included in the study were almost 276,000 children conceived by IVF and more than 2.2 million other children; 321 cancers were detected among the children conceived…

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Colorado drug takes aim at cancer metastasis

IMAGE: Heide Ford, Ph.D., and colleagues show that targeting SIX1/EYA may stop breast cancer metastasis. view more  Credit: University of Colorado Cancer Center Many cancers are relatively harmless at their site of origin, and it is only when they metastasize to sites like the brain, bones, lungs, and liver that they become especially dangerous. And so,…

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