Enzyme may indicate predisposition to cardiovascular disease

Measuring the blood plasma levels of an enzyme called PDIA1 could one day become a method of diagnosing a person’s predisposition to cardiovascular disease even if they are healthy, i.e., not obese, diabetic or a smoker, and with normal cholesterol. This is suggested by a study published in the journal Redox Biology by Brazilian researchers…

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2 catheters originally developed by Dr. Riyaz Bashir receive premarket clearance by FDA

Credit: Thrombolex, Inc. (Philadelphia, PA) — The U.S. Food and Drug Administration (FDA) has granted premarket notification clearance for two catheters invented by Riyaz Bashir, MD, FACC, RVT, Professor of Medicine at the Lewis Katz School of Medicine at Temple University (LKSOM) and Director of Vascular and Endovascular Medicine at Temple University Hospital, and Nicholas…

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IU researchers develop electric field-based dressing to help heal wound infections

IMAGE: Chandan Sen, PhD view more  Credit: Indiana University School of Medicine Researchers at Indiana University School of Medicine have found a way to charge up the fight against bacterial infections using electricity. Work conducted in the laboratories of the Indiana Center for Regenerative Medicine and Engineering, Chandan Sen, PhD and Sashwati Roy, PhD has led…

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Clinical trial at IU School of Medicine improves treatment of genetic rickets

IMAGE: Erik Imel, MD view more  Credit: Indiana University School of Medicine A new study shows a drug developed in conjunction with investigators at Indiana University School of Medicine to alleviate symptoms of a rare musculoskeletal condition is significantly more effective than conventional therapies. The findings are published in Lancet. X-linked hypophosphatemia, or XLH, is a…

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ACR statement on CMS Medicare Advantage final rule

ATLANTA — In August 2018, the CMS announced that Medicare Advantage (MA) plans would be allowed to utilize step therapy for Part B drugs. The American College of Rheumatology (ACR) expressed strong concerns about this proposal. The rheumatology community received some good news in this week’s final rule from CMS, which makes changes to the…

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Early dengue virus infection could «defuse» zika virus

«We now know for sure that Zika virus infection during pregnancy can affect the unborn foetus in such a way that the child develops microcephaly and other severe symptoms,» explains Prof Felix Drexler, a virologist at the Charité who has been developing diagnostic tests for Zika and other viruses at the DZIF. Just a few…

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Cancer drug could be repurposed to provide treatment for brain aneurysms

IMAGE: A 3D reconstruction of an angiogram showing the aneurysm circled in red. view more  Credit: Taken directly from paper published in American Journal of Human Genetics, May 2019 Brain aneurysms are relatively common, affecting around 2% of the general population Carrying a high risk of death, they can only be treated with difficult surgical procedures…

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A PCR statement on behalf of PCR and the EAPCI

Paris, France, 21 May 2019. Heart failure is a common cardiovascular disorder with ominous prognosis despite significant therapeutic advances. Mitral regurgitation (MR, leaking of the mitral valve within the heart) affects at least 50% of patients with heart failure and is independently associated with worse prognosis. Timely diagnosis is essential, and management is complex, requiring…

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PCR statement on evolving indications for transcatheter aortic valve implantation

Paris, France, 21 May 2019. Severe symptomatic aortic stenosis, a degenerative disease-causing calcification and immobility of the aortic valve leaflets leading to left ventricular outflow obstruction, is the most common valve lesion leading to intervention in Europe and the USA. Symptoms include heart failure, syncope and angina, and have a dismal prognosis if left untreated.…

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Announcing updates to PCR-EAPCI Textbook

A new update to the PCR-EAPCI Textbook for EuroPCR 2019 features new chapters on invasive physiological assessment of coronary disease, and the role of imaging in CTO intervention. It includes updates to 15 chapters including bifurcation lesions and left main coronary artery disease. Additional updates and new chapters are planned to coincide with the ESC…

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