A phase 1/2 trial involving 1,077 healthy adults found that the vaccine induced strong antibody and T cell immune responses up to day 56 of the ongoing trial. These responses may be even greater after a second dose, according to a sub-group study of 10 participants Compared to the control group (given a meningitis vaccine),…
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Researchers at EPFL are able to get paralyzed rodents walking again by stimulating the animals’ damaged spinal cords. This promising treatment has already helped paraplegics regain mobility during clinical trials at Lausanne University Hospital (CHUV). Now, using artificial intelligence, the researchers can pinpoint which neurons are involved in the gait reacquisition process. The results, which…
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If you’ve ever wondered why we get goosebumps, you’re in good company — so did Charles Darwin, who mused about them in his writings on evolution. Goosebumps might protect animals with thick fur from the cold, but we humans don’t seem to benefit from the reaction much — so why has it been preserved during…
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Phase 2 randomised controlled trial of a recombinant adenovirus type-5-vectored COVID-19 vaccine (Ad5-vectored COVID-19 vaccine) was conducted in China in April 2020 and involved more than 500 people The primary objective of the study was to evaluate the immune response and safety of the vaccine, and to determine the most suitable dose for a phase…
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PROVIDENCE, R.I. [Brown University] — Which sleep stage is most important for learning: REM or non-REM? Does sleep improve learning by enhancing skills while people snooze, or by cementing those skills in the brain so that they’re less likely to forget them? Do these processes occur every time someone sleeps, or only after they have…
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Boston, Mass. — In the early days of the COVID-19 pandemic, the disease was characterized by many as a flu-like respiratory infection mainly affecting the lungs. Now, physicians recognize that the coronavirus can impact organs throughout the body. In a collaboration among physicians at Beth Israel Deaconess Medical Center (BIDMC) and Columbia University Irving Medical…
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A replicating RNA vaccine, formulated with a lipid-based nanoparticle emulsion that goes by the acronym LION, produces antibodies against the COVID-19 coronavirus in mice and primates with a single immunization. These antibodies potently neutralize the virus. The effects occurred within two weeks after administration through injection into a muscle. The level of antibodies generated was…
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As demand for coronavirus testing surges around the nation, laboratories that process samples are again experiencing backlogs that have left anxious patients and their doctors waiting days — sometimes a week or more — for results. At the city and state levels, testing delays could mask persistent rises in case numbers and could cloud ways to combat the…
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ADEJE, Spain — Music blared from a beachfront cafe along the normally bustling southwestern coast of Tenerife, the largest of Spain’s Canary Islands. But several tables sat empty, a month after a Covid-19 lockdown had ended, and the doors to many resorts remained shut. Though tourism is returning to southern Europe — stretching from Portugal…
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Here’s what you need to know: ImageMembers of the Wisconsin National Guard organizing tests for the coronavirus in Milwaukee on Friday.Credit…Joshua Lott for The New York Times The White House pushes to eliminate billions from a relief proposal drafted by Senate Republicans. The Trump administration has balked at providing billions of dollars to fund coronavirus…
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