Decoding cellular signals linked to hypospadias

Daniel Casella, M.D., a urologist at Children’s National, was honored with an AUA Mid-Atlantic Section William D. Steers, M.D. Award, which provides two years of dedicated research funding that he will use to better understand the genetic causes for hypospadias. With over 7,000 new cases a year in the U.S., hypospadias is a common birth…

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Vanderbilt University to develop and test ‘safe harbor’ standards of care

A team of researchers from Vanderbilt University’s schools of Law, Medicine and Management has received a five-year research grant from the Agency for Healthcare Research and Quality of the Department of Health and Human Services to develop and test «safe harbor» standards of care based on scientific evidence. A goal of the project is to…

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Light, physical activity reduces brain aging

(Boston)—Incremental physical activity, even at light intensity, is associated with larger brain volume and healthy brain aging. Considerable evidence suggests that engaging in regular physical activity may prevent cognitive decline and dementia. Active individuals have lower metabolic and vascular risk factors and these risk factors may explain their propensity for healthy brain aging. However, the…

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Study: Opioid dose variability may be a risk factor for opioid overdose

Patients prescribed opioid pain medications whose doses varied over time were 3 times more likely to experience an overdose than patients prescribed stable opioid doses, according to an observational study from Kaiser Permanente published today in JAMA Network Open. The study also showed that patients who discontinued long-term opioid therapy for 3 or more months…

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Study finds that quitting smoking during pregnancy lowers risk of preterm births

There is an important association between maternal cigarette smoking cessation during pregnancy and risk of preterm birth, according to a new Dartmouth-led study published in JAMA Network Open. The negative health impacts of cigarette smoking during pregnancy—which include low birth weight, delayed intrauterine development, preterm birth, infant mortality, and long-term developmental delays—are well known. In…

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Using Edge AI to listen to the ‘silent voices’ of cattle

IMAGE: This is an overview of cattle observing systems equipped with a ‘Sense and Think Collar’. view more  Credit: Research Center for the Earth Inclusive Sensing Empathizing with Silent Voices A joint project team led by Tokyo Institute of Technology (hereinafter, «Tokyo Tech»), Shinshu University and Information Services International-Dentsu, Ltd. (hereinafter, «ISID») developed cattle observing systems…

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On-chip drug screening for identifying antibiotic interactions in eight hours

IMAGE: This is the back cover image for the Lab on a Chip. view more  Credit: KAIST A KAIST research team developed a microfluidic-based drug screening chip that identifies synergistic interactions between two antibiotics in eight hours. This chip can be a cell-based drug screening platform for exploring critical pharmacological patterns of antibiotic interactions, along with…

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Collecting the right quantity of evidence: How the brain makes a difficult decision

IMAGE: The main conclusions of the two studies are illustrated in this cartoon, where the rat must identify the texture as grooved or smooth. The first Current Biology study identified the… view more  Credit: Mathew Diamond, SISSA New research conducted in the Cognitive Neuroscience group of SISSA shows that a perceptual decision — recognizing an object…

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