Research reveals role of fat storage cells in anti-obesity intervention

HUNTINGTON, W.Va. — New research from a team at the Marshall University Joan C. Edwards School of Medicine establishes a role of adipocyte Na/K-ATPase signaling in worsening obesity and its companion diseases, including neurodegeneration and non-alcoholic steatohepatitis (NASH), that was enhanced by specific targeting of NaKtide, an antagonist of Na/K-ATPase signaling, to the adipocyte. The…

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A new way to predict complications after larynx cancer surgery

IMAGE: Rebecca Hoesli, M.D., and Matthew Spector, M.D., evaluate an image from the study view more  ANN ARBOR, Michigan — A technique that illuminates blood flow during surgery predicted which head and neck cancer patients were likely to have issues with wound healing. It could enable surgeons to make adjustments during surgery or recovery to improve…

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Prescription drug costs steadily soar, yet price transparency is lacking

LA JOLLA, CA – After reviewing tens of millions of insurance claims for the country’s 49 most popular brand-name prescription drugs, a team from Scripps Research Translational Institute found that net prices rose by a median of 76 percent from January 2012 through December 2017—with most products going up once or twice per year. The…

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ASCO: Finally, a tool to predict response to chemotherapy before bladder cancer surgery

IMAGE: Thomas Flaig, MD, and colleagues show that COXEN may predict which patients will respond to chemotherapy before bladder cancer surgery view more  Credit: University of Colorado Cancer Center University of Colorado Cancer Center led clinical trial data show that a predictive tool called COXEN may show which bladder cancer patients will respond to pre-surgical chemotherapy,…

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Astrocytes protect neurons from toxic buildup

Astrocytes are overtaxed neurons’ pit crew. The brain cells collect damaged lipids secreted by hyperactive neurons, then recycle those toxic molecules into energy, researchers at the Howard Hughes Medical Institute’s Janelia Research Campus report May 23, 2019, in the journal Cell. It’s a mechanism to protect neurons from the damaging side effects of overactivity. And…

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A small electrical zap to the brain could help you retrieve a forgotten memory

IMAGE: This is Jesse Rissman in his UCLA office. view more  Credit: Stuart Wolpert/UCLA A study by UCLA psychologists provides strong evidence that a certain region of the brain plays a critical role in memory recall. The research, published in the Journal of Cognitive Neuroscience, also shows for the first time that using an electrical current…

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Can cannabinoids help treat obsessive-compulsive disorder?

IMAGE: Cannabis and Cannabinoid Research is the premier journal dedicated to the scientific, medical, and psychosocial exploration of clinical cannabis, cannabinoids, and the biochemical mechanisms of endocannabinoids. For more information, visit… view more  Credit: ©2012, Mary Ann Liebert, Inc., publishers New Rochelle, NY, May 30, 2019—The body’s endocannabinoid system, due to the critical role it plays…

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