No evidence blanket ‘do-not-resuscitate’ orders for COVID-19 patients are necessary

DALLAS, May 22, 2020 — It’s inappropriate to consider blanket do-not-resuscitate orders for COVID-19 patients because adequate data is not yet available on U.S. survival rates for in-hospital resuscitation of COVID-19 patients and data from China may not relate to U.S. patients, according to a new article published today in Circulation: Cardiovascular Quality and Outcomes,…

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Glucose levels linked to maternal mortality even in non-diabetic women

An elevated pre-pregnancy hemoglobin A1c—which measures average blood glucose concentration—is associated with a higher risk of adverse pregnancy outcomes even in women without known diabetes, according to a new study published this week in PLOS Medicine by Joel Ray of ICES and the University of Toronto, Canada, and colleagues. Diabetes mellitus and obesity are both…

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Blood test could predict diabetes years before it strikes

Scientists have identified metabolites in the blood that accurately predict whether a woman will develop type 2 diabetes after experiencing a transient form of illness during pregnancy. This discovery could lead to a test that would help doctors identify patients at greatest risk and help them potentially avert the disease through interventions including diet and…

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Kidney transplants: Better results can be inferred from a larger number of cases

In complex operations, is there a correlation between the volume of service provided per hospital and the quality of the treatment outcome? This question is addressed in eight commissions on minimum volumes that the Federal Joint Committee (G-BA) has issued to the Institute for Quality and Efficiency in Health Care (IQWiG). The IQWiG report is…

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No improvement in death rate for COVID-19 patients who received hydroxychloroquine

Boston, MA — A research team led by investigators from Brigham and Women’s Hospital has evaluated real-world evidence related to outcomes for COVID-19 patients who were treated with hydroxychloroquine or chloroquine analogues (with or without a macrolide). Investigators found no evidence that either drug regimen reduced the death rate among patients. Patients treated with hydroxychloroquine…

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‘Time is vision’ after a stroke

A person who has a stroke that causes vision loss is often told there is nothing she can do to improve or regain the vision she has lost. New research from the University of Rochester, published in the journal Brain, may offer hope to stroke patients in regaining vision. The Rochester team found that survivors…

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When developing vaccines against COVID-19, ‘fast is slow, and slow is fast’

Bypassing clinical trials for a potential SARS-CoV-2 vaccine would be «catastrophic,» says Science Advances deputy editor Douglas Green in this Editorial. Instead, it’s vital to take time to ensure any vaccine candidate’s safety and investigate potential adverse effects, he says. A vaccine able to trigger strong neutralizing antibody responses in clinical tests will still not…

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