Chemical modifiers tag-team to regulate essential mechanism of life

SAN FRANCISCO, CA—May 2, 2019— Scientists at the Gladstone Institutes have made a key observation about one of the most fundamental biological processes: gene transcription. A gene’s job is to provide a cell with the instructions to create a specific protein. The first step of this process is called transcription, during which the DNA is…

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Up Next: Patti Harrison Bucks Transgender Stereotypes, One Joke at a Time

Name: Patti Harrison Age: 28 Hometown: Orient, Ohio Now lives: In a two-bedroom house in the Echo Park neighborhood of Los Angeles that she shares with a roommate. Claim to fame: Ms. Harrison is an actress, comedy writer and screwball performer who doesn’t take her rising profile in Hollywood too seriously. She appeared in a…

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There Are New Options in Trans Underwear

Image Carmen Liu’s first lingerie fashion show in London.CreditAna Cuba for The New York Times On a recent Thursday in London, a group of models strutted down the catwalk to “Woman’s World,” by Cher, donning matching lacy thong and bra sets, which they tastefully accented with silky robes. They were all trans women, and the…

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Medical News Today: Pain at big toe joint: Everything you need to know

People may experience pain at the big toe joint as a result of many common problems, including arthritis, injuries, and bunions. The pain can make everyday activities, including walking, more challenging. The metatarsophalangeal (MTP) joint attaches the big toe to the foot. This joint is vital for supporting the body and allowing the toe to…

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Trump Administration Files Formal Request to Strike Down All of Obamacare

The Trump administration formally declared its opposition to the entire Affordable Care Act on Wednesday, arguing in a federal appeals court filing that the signature Obama-era legislation was unconstitutional and should be struck down. Such a decision could end health insurance for some 21 million Americans and affect many millions more who benefit from the…

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Does Testosterone Really Give Caster Semenya an Edge on the Track?

The Court of Arbitration for Sport in Zurich has ruled that women with very high testosterone levels — far above the normal range — cannot compete against other women in races from 400 meters to one mile unless they take drugs to suppress production of the hormone. The ruling prevents Caster Semenya, 28, an elite…

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Corinne Cobson, Designer With a Rock ’n’ Roll Edge, Dies at 62

Corinne Cobson, the French fashion designer whose self-assured clothing for women gained acclaim in the 1980s and ’90s, died on April 16 at a clinic in Saint-Cloud, a suburb of Paris. She was 62. Her husband, Tanguy Loyzance, a photographer, said the cause was lung cancer. Ms. Cobson’s designs were distinguished by their rock ’n’…

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Premature Birth Raises Risk of Kidney Disease

Premature birth increases the risk for chronic kidney disease later in life, a new study reports. Researchers used a database of 4,186,615 singleton live births in Sweden from 1973 to 2014, following the people into mid-adulthood. The analysis, in BMJ, found 4,305 cases of chronic kidney disease. Birth before 37 weeks of gestation was associated…

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